Results 31 to 40 of about 48,481 (274)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt +2 more
wiley +1 more source
Concepts and Challenges of Biosimilars in Breast Cancer: The Emergence of Trastuzumab Biosimilars
Pharmaceutics, 2018 With the development of anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibodies, trastuzumab-based therapy has become the standard of care among patients with early or advanced HER2-positive breast cancer. However, real-world data have
Alina Uifălean +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Psychological safety (PS) is essential for teamwork, communication, and patient safety in complex healthcare environments. In pediatric oncology, interprofessional collaboration occurs under high emotional and organizational demands. Low PS may increase stress, burnout, and adverse events.
Alexandros Rahn +4 more
wiley +1 more source
Biosimilars: New guns for the treatment of rheumatological patients? [PDF]
Beyond Rheumatology, 2019 The advent of biological therapies in 2000s has represented a real revolution in the treatment of patients affected by rheumatic diseases, but biosimilars represent nowadays a further revolution both from an economic point of view and for the ...
Daniela Marotto +2 more
doaj +1 more source
Primerjalna književnost, 2019 This paper draws on the poetic concept of the oneness of the self and the world, as elaborated through Coleridge’s reading of German romantic philosophers by the poet William Wordsworth. In his poem “Prelude” he rejects simple materialism and simple spiritualism, just as Schelling rejected the extreme views that the spiritual self creates the world or ...
openaire +3 more sources
EAGLE ISS - A modular twin-channel integral-field near-IR spectrograph
, 2010 The ISS (Integral-field Spectrograph System) has been designed as part of the EAGLE Phase A Instrument Study for the E-ELT. It consists of two input channels of 1.65x1.65 arcsec field-of-view, each reconfigured spatially by an image-slicing integral ...
Evans, C. J. +5 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Interchangeability of Fluconazole Drugs
Регуляторные исследования и экспертиза лекарственных средств, 2018 Fluconazole – an antifungal agent belonging to the chemical class of triazole derivatives – is represented in the Russian pharmaceutical market by a large number of generic drugs. An important issue of rational pharmacotherapy is the demonstration of the
N. D. Bunyatyan +3 more
doaj +1 more source
Experimental Evaluation of Interchangeability in Soft CSPs [PDF]
, 2006 In [8], Freuder defined interchangeability for classical Constraint Satisfaction Problems (CSPs). Recently [2], we extended the definition of interchangeability to Soft CSPs and we introduced two notions of relaxation based on degradation # and on ...
Boi Faltings +2 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source