Results 71 to 80 of about 48,349 (272)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Apollo LM and CSM S-band antenna tracking studies. CSM-HGA interchangeability study antenna and RF circuitry analysis [PDF]
Mathematical model for radio frequency circuitry of Apollo high gain antenna ...
Osborn, J. D.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Patent Scope and Innovation in the Software Industry [PDF]
, 2001 Software patents have received a great deal of attention in the academic literature. Unfortunately, most of that attention has been devoted to the problem of whether software is or should be patentable subject matter.
Cohen, Julie E., Lemley, Mark A.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Synonymous Structures in English Syntax
Armenian Folia Anglistika, 2018 Synonymy is one of the most important sources of the wealth of language and is closely related to the problems of stylistics, speech culture, language changes and language improvements.
Jemma Militonyan
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
SMS power and grounding. CEI part 1: Detail specification, type 1 data [PDF]
This specification establishes the requirements for performance, design, test, and qualification of the SMS total power and grounding system. This is defined as designing a new PDU to be useable for SMS adding FBCS and modifying and adding to the OAS ...
core +1 more source
Determination of water quality in lakes by biological indices [PDF]
, 1980 Some problems of evaluation of water quality by biological indices which can be applied in the practice of ecological monitoring on water bodies are considered in this report.
Nikolaev, I.I.
core