Results 81 to 90 of about 48,481 (274)

Determination of water quality in lakes by biological indices [PDF]

open access: yes, 1980
Some problems of evaluation of water quality by biological indices which can be applied in the practice of ecological monitoring on water bodies are considered in this report.
Nikolaev, I.I.
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Green Hydrogen Blending into the Tunisian Natural Gas Distributing System

open access: yesHydrogen
It is likely that blending hydrogen into natural gas grids could contribute to economy-wide decarbonization while retaining some of the benefits that natural gas networks offer energy systems.
Hadhami Bdioui   +3 more
doaj   +1 more source

Authorisation of Non-Innovator Biotherapeutic (Biosimilar) Products in the USA

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2019
European competent authorities began to elaborate scientific principles of development of non-innovator biotherapeutic (biosimilar) products in the early noughties, and in 2009 these principles were approved at the WHO International Conference in Seoul ...
A. A. Soldatov   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Interchange systems. Interchanges. Used terminology

open access: yesDorogi i mosti
Summary Introduction. In the introduction to the paper, the common questions concerning the assurance of the terminological congruence of national standards’ provisions, when being harmonized, with provisions of regional or international standards were outlined and also important sources of appropriate regional information in the sector of the ...
openaire   +1 more source

SMS power and grounding. CEI part 1: Detail specification, type 1 data [PDF]

open access: yes
This specification establishes the requirements for performance, design, test, and qualification of the SMS total power and grounding system. This is defined as designing a new PDU to be useable for SMS adding FBCS and modifying and adding to the OAS ...

core   +1 more source

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