Results 51 to 60 of about 212,741 (266)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The learning cost of interest rate reversals [PDF]

open access: yesJournal of Monetary Economics, 2006
Abstract Many central banks in many time periods have sought to avoid interest rate reversals, but at present there is no good explanation of this phenomenon. Our analysis identifies a new learning cost associated with reversing the interest rate.
openaire   +2 more sources

So.cl: An Interest Network for Informal Learning

open access: yesProceedings of the International AAAI Conference on Web and Social Media, 2021
Web search engines emerged prior to the dominance of social media. What if we imagined search as integrating with social media from the ground up? So.cl is a web application that combines web browsing, search, and social networking for the purposes of sharing and learning around topics of interest.
Shelly Diane Farnham   +4 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Effectiveness of lab-work learning environments in and out of school: A cluster randomized study [PDF]

open access: yes, 2017
The issue of how to increase student motivation and achievement in science subjects is considered to be a major challenge in modern school systems. Lab-work learning environments in which students get direct (hands-on) experience with science content ...
Rehm, Markus   +7 more
core   +1 more source

Dampak Model Pembelajaran Auditory, Intellektualy, Repatition (AIR) terhadap Minat Belajar Siswa

open access: yesCakrawala: Jurnal Pendidikan, 2018
The purpose of this research is to know the impact of learning model of Auditory, Intellectual, Repatition (AIR) on the interest of learning science subjects in class III SDN 02 Banjaran.
Reza Miftah Rizkiardi   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Contextualized Question-Embedded Video-Based Teaching and Learning Tool: A Pathway in Improving Students’ Interest and Mathematical Critical Thinking Skills [PDF]

open access: yes, 2023
Filipino students exhibit lower levels of performance in mathematics and science competency compared to neighboring countries based on national and international surveys.
Rose R. Andrade, Jeerhic S. Malaluan
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

AR moulded-objects performing Giuseppe Verdi's 200th birthday

open access: yesArcheomatica, 2014
"Muri e Divisioni" è una mostra collettiva di arte contemporanea. Una call for artists è stata organizzata da Accademia delle Arti di Macerata, un'organizzazione locale no-profit composta da 40 artisti, per raccogliere opere adeguate per la mostra.
Giuliana Guazzaroni, Mirco Compagno
doaj  

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