Results 61 to 70 of about 6,653,655 (272)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Complement at the Nano–Neuroimmune Interface: A Hypothesis-Driven Perspective on Opioid Use Disorder

Immuno
The complement system is a central component of innate immunity with established roles in host defense and emerging functions in neurodevelopment, synaptic remodeling, and neuroimmune communication within the central nervous system (CNS).
Alexander Jacob, Harbir Singh, Poolakkad S. Satheeshkumar, Aum Champaneri, Rahul K. Das, Ravi K. Aalinkeel, Supriya D. Mahajan, Jessy J. Alexander   +7 more
doaj   +1 more source

Nouns for visual objects: A hypothesis of the vision-language interface

Language Sciences, 2019
Abstract We propose an interpretation of the vision process and a structural analysis of nouns and nominal reference which make it possible to relate the visual/cognitive and the linguistic encapsulation of objecthood in a rigorous way. The result of this integrated hypothesis is a predictive account of possible and impossible nouns lexicalizing ...
Francesco-Alessio Ursini, Paolo Acquaviva   +1 more
openaire   +3 more sources

A seção de Criação na revista Interface: vinte anos de experimentação

, 2017
Para celebrar os vinte anos da revista Interface, a equipe de Criação mergulhou no conjunto de materiais que foram publicados na seção de Criação desde o primeiro número da revista.
Eliane Dias de Castro, de Almeida, Eduardo Augusto Alves, Silva, Juliana Araújo [UNESP], Quarentei, Mariangela Scaglione, Mariangela Scaglione Quarentei, Ricardo Rodrigues Teixeira, Lima, Elizabeth Maria Freire Araújo, Teixeira, Ricardo Rodrigues, Gisele Dozono Asanuma, de Castro, Eliane Dias, Elizabeth Maria Freire Araújo Lima, Eduardo Augusto Alves de Almeida, Renata Monteiro Buelau, Buelau, Renata Monteiro, Juliana Araújo Silva, Asanuma, Gisele Dozono   +15 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Haustorium Formation in Medicago truncatula Roots Infected by Phytophthora palmivora Does Not Involve the Common Endosymbiotic Program Shared by Arbuscular Mycorrhizal Fungi and Rhizobia

Molecular Plant-Microbe Interactions, 2015
In biotrophic plant-microbe interactions, microbes infect living plant cells, in which they are hosted in a novel membrane compartment, the host-microbe interface.
Rik Huisman, Klaas Bouwmeester, Marijke Brattinga, Francine Govers, Ton Bisseling, Erik Limpens   +5 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Global rescue of defects in HIV-1 envelope glycoprotein incorporation: implications for matrix structure. [PDF]

PLoS Pathogens, 2013
The matrix (MA) domain of HIV-1 Gag plays key roles in membrane targeting of Gag, and envelope (Env) glycoprotein incorporation into virions. Although a trimeric MA structure has been available since 1996, evidence for functional MA trimers has been ...
Philip R Tedbury, Sherimay D Ablan, Eric O Freed   +2 more
doaj   +1 more source

hypr: An R package for hypothesis-driven contrast coding

Journal of Open Source Software, 2020
The hypr package in R provides the researcher with a straightforward interface to generate contrast matrices from research hypotheses and the reverse. It can be used to derive contrast matrices for custom research hypotheses and as an instructional tool ...
M. Rabe, Shravan Vasishth, S. Hohenstein, Reinhold Kliegl, D. Schad   +4 more
semanticscholar   +1 more source

Experimental depiction of the hypothesis of flake-like wear debris generation in rolling contact fatigue of the rail wheel contact interface

, 2016
Flake-like particles represent a common type of wear debris generated during the rolling contact fatigue wear test using a twin-disc test rig. It is argued that these flake-like particles are generated during the delamination process due to plastic shear
De Pellegrin, Dennis V., Athukorala, Asitha   +1 more
core   +1 more source