Results 151 to 160 of about 1,206,341 (327)

Interferon-gamma release assays versus tuberculin skin test for latent tuberculosis infection positivity among healthcare workers and first responders: a systematic review and meta-analysis [PDF]

Hamoud Alahmari, Lisa Hanson, Peter Kelley, Jo Spong, Adriana Milazzo, George Mnatzaganian   +5 more
openalex   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Diagnostic utility of quantitative interferon-gamma release assays in elderly patients with tuberculosis. [PDF]

Microbiol Spectr
Mutoh Y, Minato Y, Kawamoto Y, Hanai S, Umemura T, Suzuki H, Nishina Y, Hiramitsu K, Ichihara S, Hagimoto S, Fukihara J, Sasano H, Kataoka K, Kimura T, Doi Y.   +14 more
europepmc   +1 more source

Performance of interferon-gamma-inducible-protein-10 in the diagnosis of pulmonary tuberculosis among HIV patients [PDF]

Isa Musa Wasagu, Alakija Kazeem Salami, AE Fawibe, Aminu Abbas, Biliaminu Sikiru Abayomi, Yusuff Jameelu-Deen Omokunmi, Muhammad Makusidi, Adebayo Taiwo Azeez, Nasir Altine Dankiri, Umar Babangida Basihr, Yakubu Egigogo Raji   +10 more
openalex   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy

Advanced Science, EarlyView.
Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan, Zifan Pei, Jie Wu, Nan Jiang, Qian Li, Yuqi Yang, Jie Cao, Yechen Huang, Shumin Sun, Qialu Du, Zhicheng Liu, Lin Zhang, Fei Gong, Jinhua Zhou, Liang Cheng   +14 more
wiley   +1 more source

Interferon gamma applied ex vivo restores function to neutrophils from critically ill patients. [PDF]

Thorax
Lake CJ, Scott J, Ruchaud-Sparagano MH, Thompson JH, Dewar F, Yarova P, Funston W, Davidson RC, Musgrave KM, Wright SE, Clement I, Roy AI, Sendama W, Powell J, Brooks D, Lin CMA, Davies K, Hellyer TP, Rostron AJ, Simpson AJ.   +19 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

ATR-FTIR Spectroscopy for Detection of Anti-interferon-Gamma Autoantibodies. [PDF]

ACS Omega
Hongsa C, Wongwattanakul M, Chatchawal P, Srisai P, Chetchotisakd P, Anunnatsiri S, Manbenmad V, Lertmemongkolchai G, Phanabamrung S, Nithichanon A.   +9 more
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source