Results 171 to 180 of about 116,104 (295)

Interferon-gamma Release Assay-positive Granulomatous Interstitial Nephritis in a Patient with a History of Diffuse Large B Cell Lymphoma. [PDF]

Intern Med, 2023
Suehiro Y, Ueda H, Motohashi S, Honma S, Nobayashi H, Ueda R, Maruyama Y, Horino T, Ogasawara Y, Joh K, Tsuboi N, Yokoo T.   +11 more
europepmc   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

A novel non-invasive diagnostic approach based on urine and blood: a cross-sectional study combining lipoarabinomannan antigen and interferon-gamma release assay for active tuberculosis. [PDF]

Front Immunol
Cai L, Zhu M, Fang T, Peng Q, Dai L, Shao Y, Liu L.   +6 more
europepmc   +1 more source

Prevalence of Tuberculosis Infection among Adults of Thiruvananthapuram District of Kerala as Measured by Interferon Gamma Release Assay - A Cross-Sectional Study. [PDF]

Indian J Community Med, 2022
Mohan A, Indu PS, Nair S, Rakesh PS, Saradadevi KL, Rajahamsan J.   +5 more
europepmc   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

A Case of Advanced Urothelial Carcinoma Requiring Treatment Following a Positive Interferon-Gamma Release Assay Prior to Avelumab Administration. [PDF]

IJU Case Rep
Odagiri Y, Hiyama Y, Ishida U, Nishiyama N, Yamamoto Y, Kitamura H.   +5 more
europepmc   +1 more source

Interferon Gamma Release Assay Results and Testing Trends Among Patients Younger Than 2 Years Old at Two US Health Centers. [PDF]

Pediatr Infect Dis J, 2023
Tabatneck ME, He W, Lamb GS, Sun M, Goldmann D, Sabharwal V, Sandora TJ, Haberer JE, Campbell JI.   +8 more
europepmc   +1 more source

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Use of interferon-gamma release assay (IGRA) and CXCL-10/IP-10 for latent tuberculosis infection (LTBI) screening in chronic kidney disease and hemodialysis patients. [PDF]

BMC Infect Dis
da Silva JCB, Vieira NB, Ribeiro-Alves M, de Almeida Ribeiro RS, da Silva Lemos CC, Mendes R, Gomes CLR, Santos AP, Suassuna JH, Bregman R, Rodrigues LS.   +10 more
europepmc   +1 more source

scResponse: A Rank‐Based Method for Identifying Cell States That Contribute to Immunotherapy Response by Single‐Cell Data

Advanced Science, EarlyView.
Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong, Haijun Huang, Yuxiu Wang, Bo Jiang, Yuzheng Chen, Huanhuan Xu, Jing Ren, Shengnan Guo, Tianhao Li, Mingjie Zhang, Tianyu Zhai, Wenbo Yang, Kaidong Liu, Cheng Lyu, Jingxuan Kang, Mingshuo Zhang, Yupeng Lu, Binghui Si, Shujun Cao, Dandan Xu, Zong Chen, Dapeng Hao   +21 more
wiley   +1 more source