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BMEMat, EarlyView.This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li +9 more
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Interferon-Gamma Release Assays
Clinics in Laboratory Medicine, 2014Diagnosis of latent tuberculosis infection (LTBI) should be targeted toward individuals and groups with high risk of progression to active tuberculosis (TB). Low-risk populations should not be screened. Interferon-gamma release assays (IGRAs) perform as well or better than the tuberculin skin test in most targeted populations.
Robert Belknap, Charles L Daley
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Interferon gamma release assays: principles and practice
Enfermedades Infecciosas Y Microbiología Clínica, 2010The last decade has witnessed significant advances in mycobacterial genomics and cellular research which have resulted in the development of two new blood tests, the enzyme-linked immunospot assay (ELISpot) (TSPOT.TB, Oxford Immunotec, Oxford, UK) and the enzyme-linked immunosorbent assay (ELISA) (QuantiFERON-TB Gold In-Tube, Cellestis, Carnegie ...
Ajit Lalvani, Manish Pareek
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Tuberculin skin test versus interferon-gamma release assays
Acta Clinica Belgica, 2014Dear Editor,We would like to discuss on the publication on ‘Tuberculin skin test versus interferon-gamma release assays.’1 De Keyser et al.
S S, Tin, V, Wiwanitkit
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Role of interferon-gamma release assays in healthcare workers
Journal of Hospital Infection, 2009The advent of interferon-gamma release assays (IGRAs) provides new options for detection of latent tuberculosis infection (LTBI). This is particularly relevant to healthcare workers (HCWs), who are at higher risk of infection, but who have often also been vaccinated.
J E, Swindells +3 more
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Interferon-gamma release assays and TB diagnosis
Drug and Therapeutics Bulletin, 2009Worldwide in 2007, there were an estimated 9.27 million new cases of active tuberculosis (TB) and 1.8 million deaths related to the disease. However, in most people with TB, the infection is 'latent'; the underlying cause, Mycobacterium tuberculosis, remains alive but patients are asymptomatic and non-infectious.
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Interferon-gamma release assays for tuberculosis: current and future applications
Expert Review of Respiratory Medicine, 2013Interferon-gamma release assays (IGRAs) represent the first new tool to diagnose latent tuberculosis infection for more than 100 years. They have advantages over the traditional tuberculin skin test which has a poor specificity due to false-positive responses in people who are BCG vaccinated as there is a cross-reactivity of proteins present in both ...
Muhunthan, Thillai +3 more
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