Results 91 to 100 of about 58,702 (314)
Advanced Healthcare Materials, EarlyView.Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan +10 more
wiley +1 more source
P2.045 Serial Testing with an Interferon-Gamma Release Assay in HIV-1-Infected Individuals [PDF]
Sexually Transmitted Infections, 2013 Background The clinical utility of serial screening for tuberculosis (TB) by interferon-gamma release assays has not been established in HIV-1-infected individuals. Methods In this prospective study HIV-1-infected subjects underwent repeated QuantiFERON-TB Gold In-Tube assay (QFT-GIT) testing at baseline and after 24 months to determine the rate of ...
M C Aichelburg +4 more
openaire +1 more source
PLoS ONE, 2016 Background Accurate diagnosis of latent tuberculosis infection (LTBI) is becoming increasingly concerning due to the increasing the HIV epidemic, which have increased the risk for reactivation to active tuberculosis (TB) infection.
E. Ayubi +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu +13 more
wiley +1 more source
When should you suspect tuberculosis (TB)? -- How do you evaluate persons suspected of having TB disease?
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Advanced Science, EarlyView.Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
The Turkish Journal of Gastroenterology, 2018 Background/Aims: Screening for latent tuberculosis infection is mandatory before starting anti-tumor necrosis factor therapy. New assays based on interferon-γ (IFN-γ) release have recently become available and may be more accurate.
José Luis Cabriada +7 more
doaj +1 more source
The Tohoku Journal of Experimental Medicine, 2017 Japan is still designated as a medium incidence country, worldwide. Although the definitive diagnosis of tuberculosis is made by detecting pathogen from tissue specimens, collecting those from children is physically difficult. Therefore, we must frequently depend on the results of tuberculin skin test (TST) or interferon-gamma release assay (IGRA ...
Shimizu, Hiroyuki, Mori, Masaaki
openaire +3 more sources
Latent tuberculosis infection : a guide for primary health care providers [PDF]
Tuberculosis (TB) is caused by a bacterium called Mycobacterium tuberculosis (M. tuberculosis). Not everyone infected with TB bacteria becomes sick. As a result, two TB-related conditions exist: latent TB infection (LTBI) and TB disease.
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Advanced Science, EarlyView.This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source