Results 101 to 110 of about 58,702 (314)

A comparison of intradermal test with recombinant tuberculosis allergen (diaskintest) with other immunologic tests in the diagnosis of tuberculosis infection

International Journal of Mycobacteriology, 2018
Background: The WHO strategy for eradication of tuberculosis (TB) by 2035 (The End TB Strategy) is aimed at an early and precise diagnosis and subsequent effective treatment of TB patients. Currently, there is no gold standard for the diagnosis of latent
Anna Starshinova, Viacheslav Zhuravlev, Irina Dovgaluk, Alexandr Panteleev, Vera Manina, Ulia Zinchenko, Evgenia Istomina, Maria Pavlova, Piotr Yablonskiy   +8 more
doaj   +1 more source

Comparing Interferon-Gamma Release Assays to Tuberculin Skin Test in Thai Children with Tuberculosis Exposure

PLoS ONE, 2014
Los datos sobre el rendimiento de los ensayos de liberación de interferón gamma (IGRA), QuantiFERON TB Gold In-tube (QFNGIT) y T-Spot.TB, en el diagnóstico de la tuberculosis (TB) son limitados en el sudeste asiático. Este estudio tiene como objetivo comparar los rendimientos de los dos IGRA y TST en niños tailandeses con exposición reciente a la TB ...
Tieu, Hong Van N., Suntarattiwong, Piyarat, Puthanakit, Thanyawee, Chotpitayasunondh, Tawee, Chokephaibulkit, Kulkanya, Buranapraditkun, Supranee, Sirivichayakul, Sunee, Rungrojrat, Patcharawee, Chomchey, Nitiya, Tsiouris, Simon, Hammer, Scott M., Nandi, Vijay, Ananworanich, Jintanat, Thai TB Px study group   +13 more
openaire   +5 more sources

Interferon-gamma release assays (IGRAs) - blood tests for TB infection [PDF]

Interferon-Gamma Release Assays (IGRAs) are whole-blood tests that can aid in diagnosing Mycobacterium tuberculosis infection. They do not help differentiate latent tuberculosis infection (LTBI) from tuberculosis disease.

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Multidrug-resistant tuberculosis outbreak in an Italian prison: tolerance of pyrazinamide plus levofloxacin prophylaxis and serial interferon gamma release assays

new microbes and new infections, 2016
The optimal treatment for latent tuberculosis infection (LTBI) in subjects exposed to multidrug-resistant (MDR) tuberculosis (TB) remains unclear, and the change in response of the QuantiFERON-TB Gold In-Tube (QTB-IT) test during and after treatment is ...
A. Bedini, E. Garlassi, C. Stentarelli, S. Petrella, M. Meacci, B. Meccugni, M. Meschiari, E. Franceschini, S. Cerri, A. Brasacchio, F. Rumpianesi, L. Richeldi, C. Mussini   +12 more
semanticscholar   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Self-study modules on tuberculosis [PDF]

The Self-Study Modules on Tuberculosis are a series of educational modules designed to provide information about TB in a self-study format. The series consists of a total of nine modules that are separated into two courses. The first course, Modules 1-5,

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Interferon-gamma release assay versus tuberculin skin test for latent tuberculosis infection among HIV patients in Brazil

Brazilian Journal of Infectious Diseases, 2015
Setting Patients HIV+ attending in a reference clinic, Southern Brazil. Objective To compare the interferon-gamma-release assay (IGRA – QuantiFERON® TB Gold In-Tube) with the tuberculin skin test (TST – PPD-Rt 23) for latent tuberculosis infection (LTBI)
G. B. Kussen, L. Dalla-Costa, A. Rossoni, S. M. Raboni   +3 more
semanticscholar   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Concordancia de las pruebas de tuberculina e Interferón gamma en población reclusa Concordance of tuberculin tests and Interferon gamma release assays in the prison population

Revista Española de Sanidad Penitenciaria, 2011
Objetivos: Estudiar en población penitenciaria la concordancia de la prueba de la tuberculina (PT) y las pruebas de interferón gamma (IFG). Material y métodos: Estudio prospectivo realizado en una prisión en mayo-junio de 2009.
A. Marco Mouriño, A. Orcau Palau, R. Jané Galliga, M. Escribano Ibáñez, J.A. Caylà Buqueras, N. Solé Zapata, L. del Baño Hollín, S. Quintero del Río, M.D. Ferrer Escobar, J. Mangues Bafalluy, R.A. Guerrero Moreno, V. Martín Sánchez   +11 more
doaj  

Performance of the Interferon Gamma Release Assays in Tuberculosis Disease in Children Five Years Old or Less

PLoS ONE, 2015
Interferon Gamma Release Assays (IGRAs) were developed for the indirect or immunologic diagnosis of tuberculosis infection; however, they have also been used to assist in difficult to diagnose cases of tuberculosis disease in adults, and to a lesser ...
Lin Sun, Jian-ling Tian, Q. Yin, Jing Xiao, Jie-qiong Li, Ya-jie Guo, Guo-shuang Feng, Xiao-xia Peng, Hui Qi, Fang Xu, W. Jiao, Chen Shen, A. Shen   +12 more
semanticscholar   +1 more source