Results 101 to 110 of about 98,491 (346)

Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]

, 2001
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K., Agnew A., Amory Soisson L., Aranda-Michel J., Araújo M. I., Ashton P. D., Bergquist N. R., Butterworth A. E., Butterworth A. E., Caldas I. R., Capron A., Carneiro-Santos P., Caulada-Benedetti Z., Chan M. S., Coulson P. S., de Clercq D., de Jonge N., Deelder A. M., Doetze A., Dunne D. W., Eberl M., Eberl M., Eberl M., Gryseels B, Gryseels B., Grzych J. M., Harrop R., Harrop R., Hsü S. Y., Jankovic D., Kardorff R., Kasper G., Katz N., Kuntz R. E., Mahmoud O. M., Malaquias L. C. C., Mansour M. M., Marguerite M., Medhat A., Montenegro S. M. L., Moser D., Olsen A., Omer F. M., Omer-Ali P., Pearce E. J., Pemberton R. M., Polman K., Prince A. M., Renquist D. M., Rieckmann K. H., Rocha M. O., Sadun E. H., Sadun E. H., Sher A., Smythies L. E., Sundstedt A., Tanner M., Velupillai P., Viana I. R., Viana I. R., von Lichtenberg F., von Lichtenberg F., Williams M. E., Wilson R. A., Yole D. S., Yole D. S.   +65 more
core   +2 more sources

Tuberculin Skin Testing and Treatment Modulates Interferon-Gamma Release Assay Results for Latent Tuberculosis in Migrants [PDF]

PLoS ONE, 2014
Identifying latent tuberculosis infection (LTBI) in people migrating from TB endemic regions to low incidence countries is an important control measure. However, no prospective longitudinal comparisons between diagnostic tests used in such migrant populations are available.To compare commercial interferon (IFN)-gamma release assays (IGRAs) and the ...
O'Shea, M, Fletcher, T, Beeching, N, Dedicoat, M, Spence, D, McShane, H, Cunningham, A, Wilson, D   +7 more
openaire   +5 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Telluride quantum dot-amplified immunosensor for interferon gamma – A TB antigen test biomarker

Sensing and Bio-Sensing Research
Interferon-gamma (IFN-γ) is a cytokine (i.e. a microprotein involved in cell signaling and immunomodulation) which is known to be expressed in response to Mycobacterium tuberculosis (Mtb) infections.
Sixolile Mini, Kaylin Cleo Januarie, Marlon Oranzie, Candice Cupido, Kefilwe Vanessa Mokwebo, Usisipho Feleni, Emmanuel Iwuoha   +6 more
doaj   +1 more source

O desafio de diagnosticar a infeccao tuberculosa na crianca [PDF]

, 2014
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departamento de PediatriaUNIFESP, EPM, Depto.
Succi, Regina Célia de Menezes
core   +2 more sources

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

A rare extrapulmonary manifestation of tuberculosis in a chronic kidney disease patient

Clinical Case Reports, 2023
Key Clinical Message Chronic kidney disease (CKD) and tuberculoma are two distinct medical conditions. Nonetheless, they can be related in very rare cases.
Lokesh Koumar Sivanandam, Manpreet Kaur Jhoond, Saurabh Ashok Sujanyal, Shreya Sridhar, Nathalie Nasser, Vivek Sanker, Umang Gupta   +6 more
doaj   +1 more source

Mycobacterium tuberculosis Infection in Young Children: Analyzing the Performance of the Diagnostic Tests [PDF]

, 2015
This study evaluated the performance of the Tuberculin Skin Test (TST) and Quantiferon-TB Gold in-Tube (QFT) and the possible association of factors which may modify their results in young children (0-6 years) with recent contact with an index ...
Abellana Sangrà, Rosa Mari, Antunes, Irineide Assumpçao, Ascaso Terrén, Carlos, Bührer-Sékula, Samira, 1955-, Da Silva Garrido, Marlucia, Jardim Sardinha, José Felipe, Malheiro, Adriana, Martins, Marilaine, Martínez Espinosa, Flor E., Pérez-Porcuna, Tomàs M., Quincó, Patricia   +10 more
core   +2 more sources

[Concordance of tuberculin tests and Interferon gamma release assays in the prison population].

Revista espanola de sanidad penitenciaria, 2011
To study the agreement of Tuberculin Skin Tests (TST) and Interferon Gamma Release Assays (IGRA) when screening tuberculosis infection amongst inmates recently admitted to prison.Prospective study conducted in a prison during the months of May and June 2009.
A, Marco Mouriño, A, Orcau Palau, R, Jané Galliga, M, Escribano Ibáñez, J A, Caylà Buqueras, N, Solé Zapata, L, del Baño Hollín, S, Quintero del Río, M D, Ferrer Escobar, J, Mangues Bafalluy, R A, Guerrero Moreno, V, Martín Sánchez   +11 more
openaire   +2 more sources