Results 21 to 30 of about 98,491 (346)
Diagnosis of latent Mycobacterium tuberculosis infection: tuberculin test versus interferon-gamma release [PDF]
The treatment of individuals with active tuberculosis (TB) and the identification and treatment of latent tuberculosis infection (LTBI) contacts are the two most important strategies for the control of TB. The objective of this study was compare the performance of tuberculin skin testing (TST) with QuantiFERON-TB Gold In TUBE(r) in the diagnosis of ...
Ferreira, Thaís Furtado +3 more
openaire +5 more sources
Hemodialysis acutely altered interferon-gamma release assay test result and immune cell profile
Patients receiving hemodialysis (HD) are at risk of TB development. IGRA-positive patients showed significant decrease in quantitative IGRA result with alterations in CD3+CD4+CD45RO+, NK cell, and monocyte subsets immediately upon HD procedure. Our result suggested that the timing of IGRA testing is crucial in end-stage renal disease population.
Denise Utami Putri +8 more
openaire +3 more sources
Objective: To evaluate the performance of interferon gamma release assays and tuberculin skin test in HIV-infected children and adolescents with immune reconstitution.
Keswadee Lapphra +11 more
doaj +1 more source
Cost-effectiveness of interferon gamma release assays vs tuberculin skin tests in health care workers. [PDF]
Interferon gamma release assays (IGRAs) offer alternatives to tuberculin skin tests (TSTs) for diagnosing latent tuberculosis infection (LTBI). Unlike TSTs, IGRAs require only a single patient visit and are not affected by prior BCG vaccination, providing greater specificity.
Marie A de Perio +4 more
semanticscholar +3 more sources
BackgroundHealthcare workers (HCWs) have a higher risk of latent tuberculosis infection (LTBI) and active tuberculosis than the general population.
Edinson Dante Meregildo-Rodriguez +3 more
doaj +1 more source
Performance of commerical blood tests for the diagnosis of latent tuberculosis infection in children and adolescents [PDF]
BACKGROUND: The accurate diagnosis of latent tuberculosis infection reduces the risk of progression to severe disseminated disease. However, in young children, a major limitation of the standard tuberculin skin test is that false-negative results cannot ...
B. Meccugni +10 more
core +1 more source
Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari +118 more
core +2 more sources
Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons [PDF]
BACKGROUND: Interferon-γ (IFN-γ, a type II IFN) is present in the central nervous system (CNS) under various conditions. Evidence is emerging that, in addition to its immunological role, IFN-γ modulates neuronal morphology, function, and development in ...
Bräuer, Anja U. +7 more
core +1 more source
Implementation of routine interferon-gamma release assay testing in a South London HIV cohort [PDF]
Human immunodeficiency virus (HIV) infection is a major risk factor for the development of tuberculosis (TB). Although guidelines recommend that people with HIV from high TB incidence countries and those with risk factors are screened for latent TB infection (LTBI) using interferon-gamma release assays (IGRAs), this has not been widely implemented in ...
Preeti Sandhu +3 more
openaire +4 more sources
Background and Objectives: This study aimed to evaluate the performance of a new chemiluminescent immunoassay-based tuberculosis (TB) interferon-gamma release assay (IGRA), AdvanSureI3 TB-IGRA (LG Chem Ltd., Seoul, Republic of Korea), for detecting ...
Keun Ju Kim +4 more
doaj +1 more source

