Results 51 to 60 of about 35,670 (265)

Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study

대한영상의학회지, 2021
Purpose To investigate the incidence of tuberculosis (TB) in healthcare workers (HCWs) with positive interferon-gamma release assay (IGRA) results based on chest X-ray (CXR) and CT findings and determine the role of imaging in the diagnosis of TB ...
Ye Ra Choi, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Kwang Nam Jin   +4 more
doaj   +1 more source

Landscape of TB Infection and Prevention among People Living with HIV

Pathogens, 2022
Tuberculosis (TB) is one of the leading causes of mortality in people living with HIV (PLHIV) and contributes to up to a third of deaths in this population.
Anca Vasiliu, Rebecca Abelman, Yousra Kherabi, Antonia Morita Iswari Saktiawati, Alexander Kay   +4 more
doaj   +1 more source

Tuberculin Skin Testing and Treatment Modulates Interferon-Gamma Release Assay Results for Latent Tuberculosis in Migrants [PDF]

PLoS ONE, 2014
Identifying latent tuberculosis infection (LTBI) in people migrating from TB endemic regions to low incidence countries is an important control measure. However, no prospective longitudinal comparisons between diagnostic tests used in such migrant populations are available.To compare commercial interferon (IFN)-gamma release assays (IGRAs) and the ...
O'Shea, M, Fletcher, T, Beeching, N, Dedicoat, M, Spence, D, McShane, H, Cunningham, A, Wilson, D   +7 more
openaire   +5 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Host factors associated to false negative and indeterminate results in an interferon‐γ release assay in patients with active tuberculosis

Pulmonology, 2020
Introduction Information on host factors that contribute to false negative and indeterminate results in interferon‐γ release assays (IGRA) are critical to improve the usefulness of these tests in the fight against tuberculosis (TB) epidemics.The aim of ...
J.A. Santos, R. Duarte, C. Nunes
doaj   +1 more source

Comparison of Two Commercially Available Interferon-γ Release Assays for T-Cell-Mediated Immunity and Evaluation of Humoral Immunity against SARS-CoV-2 in Healthcare Workers

Diagnostics, 2023
Cellular immunity against SARS-CoV-2 is an important component of the immune response to the virus. At present, two such tests based on interferon-gamma release (interferon-γ release assays, IGRAs) are available—Quan-T-Cell SARS-CoV-2 by EUROIMMUN and T ...
Alexandra Lochmanová, Jan Martinek, Hana Tomášková, Hana Zelená, Kersten Dieckmann, Evelin Grage-Griebenow, Eduard Ježo, Jaroslav Janošek   +7 more
doaj   +1 more source

Interferon‐Gamma Release Assays Are a Better Tuberculosis Screening Test for Hemodialysis Patients: A Study and Review of the Literature [PDF]

Canadian Journal of Infectious Diseases and Medical Microbiology, 2012
Diagnosing latent tuberculosis (TB) infection (LTBI) in dialysis patients is complicated by poor response to tuberculin skin testing (TST), but the role of interferon‐gamma release assays (IGRAs) in the dialysis population remains uncertain. Seventy‐nine patients were recruited to compare conventional diagnosis (CD) with the results of two IGRA tests ...
J Grant, J Jastrzebski, J Johnston, A Stefanovic, J Jastrabesky, K Elwood, D Roscoe, R Balshaw, E Bryce   +8 more
openaire   +3 more sources

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Antigen-Specific IP-10 Release Is a Sensitive Biomarker of Mycobacterium bovis Infection in Cattle. [PDF]

PLoS ONE, 2016
The most widely used ante-mortem diagnostic tests for tuberculosis in cattle are the tuberculin skin test and the interferon-gamma (IFN-γ) release assay, both of which measure cell-mediated immune responses to Mycobacterium bovis infection.
Sven D C Parsons, Kevina McGill, Mairead B Doyle, Wynand J Goosen, Paul D van Helden, Eamonn Gormley   +5 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source