Results 61 to 70 of about 58,702 (314)

Diagnostic usefulness of the cytomegalovirus (CMV)-specific T cell-based assay for predicting CMV infection after kidney transplant [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2020
Background/Aims We evaluated the usefulness in kidney transplant (KT) candidates of cytomegalovirus (CMV)-specific enzyme-linked immunospot (ELISPOT) assays for predicting the development of post-transplant CMV infections.
Taeeun Kim   +13 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Tuberculosis research in ASEAN countries: a bibliometric analysis

open access: yes, 2017
Introduction. Research on TB is a fundamental key in the process to eliminate this bacterial infection as a threat to global health and the analysis of the scientific output provides valuable information related to trends in time and the epidemiology of ...
cahyadin, cahyadin   +2 more
core   +1 more source

Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024

open access: yesBMC Nephrology
Objectives Tuberculosis screening in pediatric lupus nephritis (LN) patients presents unique diagnostic challenges. This study aimed to analyze the frequency of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results among children with LN and the ...
Yue Xi   +10 more
doaj   +1 more source

Aktif tüberküloz hastalarında tedavi öncesi ve tedavi sonrası Quantiferon-TB Gold Plus testi sonuçlarının değerlendirilmesi

open access: yes, 2023
Tıp Fakültesi, Tıbbi Mikrobiyoloji A.B.D. Araştırma ProjesiAraştırma Projesi elektronik ortamda bulunmaktadır.AMAÇ: Latent tüberküloz enfeksiyonu (LTBE)'nun tespiti için önemli tanı testlerinden birisi interferon-? (IFN) salım testleri(IGST)dir.
Çavuşoğlu, Cengiz
core  

Quantitative Interferon Gamma Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis: A Prospective Cohort Study.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2019
RATIONALE Development of diagnostic tools with improved predictive value for tuberculosis (TB) is a global research priority. OBJECTIVES We evaluated whether implementing higher diagnostic thresholds than currently recommended for QuantiFERON Gold-in ...
Rishi K. Gupta   +16 more
semanticscholar   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Landscape of TB Infection and Prevention among People Living with HIV

open access: yesPathogens, 2022
Tuberculosis (TB) is one of the leading causes of mortality in people living with HIV (PLHIV) and contributes to up to a third of deaths in this population.
Anca Vasiliu   +4 more
doaj   +1 more source

Performance of Tuberculin Skin Test Measured against Interferon Gamma Release Assay as Reference Standard in Children [PDF]

open access: yesTuberculosis Research and Treatment, 2014
Objectives. International guidelines differ in the threshold of tuberculin skin test (TST) induration regarded as indicatingMycobacterium (M.) tuberculosisinfection. Interferon gamma release assay (IGRA) results were used as reference to assess performance of TST induration thresholds for detection ofM.
Eisenhut, Michael, Fidler, Katy
openaire   +3 more sources

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