Results 61 to 70 of about 77,953 (304)

Apoptotic epitope-specific CD8+ T cells and interferon signaling intersect in chronic hepatitis C virus infection [PDF]

, 2015
CD8(+) T cells specific to caspase-cleaved antigens derived from apoptotic T cells represent a principal player in chronic immune activation (CIA). Here, we found that both apoptotic epitope (AE)-specific and hepatitis C virus (HCV)-specific CD8(+) T ...
Accapezzato, Daniele, Barnaba, Vincenzo, Calvo, Ludovica, Cavallari, EUGENIO NELSON, Citro, Alessandra, Coccia, Eliana M, D'Ettorre, Gabriella, DE MARZIO, Paolo, DI FILIPPO, Simona, Grazi, Gian Luca, Labbadia, Giancarlo, Martini, Helene, Martire, Carmela, Piconese, Silvia, Rizzo, Fabiana, Sette, Alessandro, Severa, Martina, Sidney, John, Vullo, Vincenzo   +18 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Characteristics of indeterminate QuantiFERON-TB Gold PLUS results in pediatric lupus nephritis at Beijing Children’s Hospital, 2023–2024

BMC Nephrology
Objectives Tuberculosis screening in pediatric lupus nephritis (LN) patients presents unique diagnostic challenges. This study aimed to analyze the frequency of indeterminate QuantiFERON-TB Gold Plus (QFT-Plus) results among children with LN and the ...
Yue Xi, Huiwen Zheng, Yonghong Wang, Yajie Guo, Jing Xiao, Feina Li, Hui Qi, Weiwei Jiao, Nan Zhou, Zhi Chen, Lin Sun   +10 more
doaj   +1 more source

Landscape of TB Infection and Prevention among People Living with HIV

Pathogens, 2022
Tuberculosis (TB) is one of the leading causes of mortality in people living with HIV (PLHIV) and contributes to up to a third of deaths in this population.
Anca Vasiliu, Rebecca Abelman, Yousra Kherabi, Antonia Morita Iswari Saktiawati, Alexander Kay   +4 more
doaj   +1 more source

EPIDEMIOLOGY OF TUBERCULOSIS IN INTERNATIONALLY DISPLACED CHILDREN RESETTLING IN HARRIS COUNTY [PDF]

, 2019
Background More than 300,000 refugees arrived in the United States (U.S.) from 2010-2015, and Texas accepts the 2nd highest number of refugees. Texas also accepts large numbers of asylees, parolees, and special immigrant visa holders.
LAMB, GABRIELLA S
core   +1 more source

Diagnosis of tuberculosis infection using interferon-γ-based assays [PDF]

, 2014
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a reliable alternative to the old tuberculin skin test (TST) for the immunodiagnosis of tuberculosis (TB) infection.
Aabye, Aichelburg, Altet-Gómez, Andersen, Arend, Baba, Bakir, Bamford, Bartalesi, Bocchino, Brock, Brock, Carmona, Casas, Chee, Choi, Clark, Cobanoglu, Connell, Connell, Davies, Detjen, Dheda, Diel, Diel, Diel, Diel, Doherty, Domínguez, Domínguez, Domínguez, Ferrara, García-Gasalla, Gardam, Goletti, Higuchi, Hill, Horsburgh, Jafari, Jafari, Jafari, Janssens, Jasmer, Jones, José Domínguez Benítez, Kampmann, Karam, Kik, Kim, Kim, Kobashi, Kobashi, Kobashi, Lalvani, Lalvani, Lalvani, Lalvani, Lalvani, Latorre, Latorre, Leidl, Leung, Liebeschuetz, Lighter, Liu, Losi, Mandalakas, Markova, Martin, Matulis, Menzies, Menzies, Metcalfe, Miguel Santín Cerezales, Millington, Mori, Nicol, Nienhaus, Pai, Pai, Panes, Patel, Ponce de León, Raby, Rangaka, Richeldi, Richeldi, Rivas, Ruhwald, Santín, Sester, Stephan, Syed Ahamed Kabeer, Takahashi, Thomas, Trajman, Tsiouris, Van Zyl-Smit, Vassilopoulos, Vincenti, Wilkinson   +100 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Chest Radiographs and CT Findings during Healthcare Workers’ Tuberculosis Screening Using Interferon- Gamma Release Assay: Retrospective Observational Study

대한영상의학회지, 2021
Purpose To investigate the incidence of tuberculosis (TB) in healthcare workers (HCWs) with positive interferon-gamma release assay (IGRA) results based on chest X-ray (CXR) and CT findings and determine the role of imaging in the diagnosis of TB ...
Ye Ra Choi, Jung-Kyu Lee, Eun Young Heo, Deog Kyeom Kim, Kwang Nam Jin   +4 more
doaj   +1 more source

Comparison of Two Commercially Available Interferon-γ Release Assays for T-Cell-Mediated Immunity and Evaluation of Humoral Immunity against SARS-CoV-2 in Healthcare Workers

Diagnostics, 2023
Cellular immunity against SARS-CoV-2 is an important component of the immune response to the virus. At present, two such tests based on interferon-gamma release (interferon-γ release assays, IGRAs) are available—Quan-T-Cell SARS-CoV-2 by EUROIMMUN and T ...
Alexandra Lochmanová, Jan Martinek, Hana Tomášková, Hana Zelená, Kersten Dieckmann, Evelin Grage-Griebenow, Eduard Ježo, Jaroslav Janošek   +7 more
doaj   +1 more source

Tuberculin Skin Tests versus Interferon-Gamma Release Assays in Tuberculosis Screening among Immigrant Visa Applicants [PDF]

Tuberculosis Research and Treatment, 2014
Objective. Use of tuberculin skin tests (TSTs) and interferon gamma release assays (IGRAs) as part of tuberculosis (TB) screening among immigrants from high TB-burden countries has not been fully evaluated.Methods. Prevalence ofMycobacterium tuberculosisinfection (MTBI) based on TST, or the QuantiFERON-TB Gold test (QFT-G), was determined among ...
Chuke, Stella O., Yen, Nguyen Thi Ngoc, Laserson, Kayla F., Phuoc, Nguyen Huu, Trinh, Nguyen An, Nhung, Duong Thi Cam, Mai, Vo Thi Chi, Qui, An Dang, Hai, Hoang Hoa, Loan, Le Thien Huong, Jones, Warren G., Whitworth, William C., Shah, J. Jina, Painter, John A., Mazurek, Gerald H., Maloney, Susan A.   +15 more
openaire   +2 more sources