Results 61 to 70 of about 98,491 (346)

Immunomodulatory Effect of Toll-Like Receptor-3 Ligand Poly I:C on Cortical Spreading Depression [PDF]

, 2009
The release of inflammatory mediators following cortical spreading depression (CSD) is suggested to play a role in pathophysiology of CSD-related neurological disorders.
Aghabarari, A., Ghaemi, A., Gorji, A., Khaleghi Ghadiri, M., Khodaie, B., Lotfinia, A.A., Lotfinia, M., Meuth, S., Sajadian, A.   +8 more
core   +2 more sources

Diagnostic usefulness of the cytomegalovirus (CMV)-specific T cell-based assay for predicting CMV infection after kidney transplant [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims We evaluated the usefulness in kidney transplant (KT) candidates of cytomegalovirus (CMV)-specific enzyme-linked immunospot (ELISPOT) assays for predicting the development of post-transplant CMV infections.
Taeeun Kim, Hyun-Jeong Lee, Sun-Mi Kim, Joo Hee Jung, Sung Shin, Young-Hoon Kim, Heungsup Sung, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim, Duck Jong Han   +13 more
doaj   +1 more source

Interferon-gamma release assays for the diagnosis of tuberculosis and tuberculosis infection in HIV-infected adults: a systematic review and meta-analysis. [PDF]

, 2014
Background: Despite the widespread use of interferon-gamma release assays (IGRAs), their role in diagnosing tuberculosis and targeting preventive therapy in HIV-infected patients remains unclear.
Muñoz López, Laura, Rigau, David, Santín Cerezales, Miguel   +2 more
core   +2 more sources

Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation.

Health Technology Assessment, 2019
BACKGROUND Interferon gamma release assays (IGRAs) are blood tests recommended for the diagnosis of tuberculosis (TB) infection. There is currently uncertainty about the role and clinical utility of IGRAs in the diagnostic workup of suspected active TB ...
Y. Takwoingi, H. Whitworth, M. Rees-Roberts, Amarjit Badhan, Christopher Partlett, N. Green, A. Boakye, Heather Lambie, L. Marongiu, M. Jit, P. White, J. Deeks, O. Kon, A. Lalvani   +13 more
semanticscholar   +1 more source

Diagnosis of tuberculosis infection using interferon-γ-based assays [PDF]

, 2014
Interferon-γ-based assays, collectively known as IFN-γ release assays (IGRAs), have emerged as a reliable alternative to the old tuberculin skin test (TST) for the immunodiagnosis of tuberculosis (TB) infection.
Aabye, Aichelburg, Altet-Gómez, Andersen, Arend, Baba, Bakir, Bamford, Bartalesi, Bocchino, Brock, Brock, Carmona, Casas, Chee, Choi, Clark, Cobanoglu, Connell, Connell, Davies, Detjen, Dheda, Diel, Diel, Diel, Diel, Doherty, Domínguez, Domínguez, Domínguez, Ferrara, García-Gasalla, Gardam, Goletti, Higuchi, Hill, Horsburgh, Jafari, Jafari, Jafari, Janssens, Jasmer, Jones, José Domínguez Benítez, Kampmann, Karam, Kik, Kim, Kim, Kobashi, Kobashi, Kobashi, Lalvani, Lalvani, Lalvani, Lalvani, Lalvani, Latorre, Latorre, Leidl, Leung, Liebeschuetz, Lighter, Liu, Losi, Mandalakas, Markova, Martin, Matulis, Menzies, Menzies, Metcalfe, Miguel Santín Cerezales, Millington, Mori, Nicol, Nienhaus, Pai, Pai, Panes, Patel, Ponce de León, Raby, Rangaka, Richeldi, Richeldi, Rivas, Ruhwald, Santín, Sester, Stephan, Syed Ahamed Kabeer, Takahashi, Thomas, Trajman, Tsiouris, Van Zyl-Smit, Vassilopoulos, Vincenti, Wilkinson   +100 more
core   +2 more sources

Validation and Clinical Application of Interferon-Gamma Release Assay for Diagnosis of Latent Tuberculosis Infection in Children

International Journal of Applied and Basic Medical Research, 2019
Background: India has the highest tuberculosis (TB) burden, accounting for one-fifth of the global incidence and two-third of the cases in Southeast Asia with an estimated 1.9 million new cases every year.
K. Benachinmardi, S. Sangeetha, M. Rao, R. Prema   +3 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Diagnosis of childhood tuberculosis and host RNA expression in Africa [PDF]

, 2014
Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with ...
Amelia C. Crampin, Andrew J. Brent, Brian Eley, Claire M. Banwell, Eamranond P, Florian Kern, George Chagaluka, Hazel M. Dockrell, Hemed Twahir, Hesseling AC, J. Anthony G. Scott, Lachlan J. Coin, Ling Ling, Martin L. Hibberd, Melissa S. Hamilton, Michael Levin, Myrsini Kaforou, Neil French, Paul R. Langford, Rachel Mlotha, Robert J. Wilkinson, Robert S. Heyderman, Sandy Pienaar, Suzanne T. Anderson, Tom H.M. Ottenhoff, Vashini Pillay, Victoria J. Wright   +26 more
core   +5 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Landscape of TB Infection and Prevention among People Living with HIV

Pathogens, 2022
Tuberculosis (TB) is one of the leading causes of mortality in people living with HIV (PLHIV) and contributes to up to a third of deaths in this population.
Anca Vasiliu, Rebecca Abelman, Yousra Kherabi, Antonia Morita Iswari Saktiawati, Alexander Kay   +4 more
doaj   +1 more source