Results 1 to 10 of about 327,168 (302)

Impending anterior ischemic optic neuropathy with elements of retinal vein occlusion in a patient on interferon for polycythemia vera [PDF]

Clinical Ophthalmology, 2012
Kelly S Rue, Louis K Hirsch, Alfredo A SadunDepartment of Neuro-Ophthalmology, Doheny Eye Institute and Keck School of Medicine, University of Southern California, Los Angeles, CA, USAAbstract: We describe the course and likely pathophysiology of ...
Rue KS, Hirsch LK, Sadun AA
doaj   +3 more sources

The treatment of hepatitis C: history, presence and future [PDF]

, 2004
The treatment of chronic hepatitis C has made remarkable progress over the past two decades. For interferon-alpha monotherapy, sustained virological response rates were between 2 and 9% in genotype 1 and between 16 and 23% in genotypes ...
Knegt, R.J. (Robert) de, Orlent, H. (Hans), Schalm, S.W. (Solko), Veldt, B.J. (Bart), Vrolijk, J.M. (Jan)   +4 more
core   +10 more sources

Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]

Vojnosanitetski Pregled, 2015
Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan, Gačević Milomir, Jović Milena, Mijušković Željko, Zečević Radoš, Zolotarevski Lidija, Jauković Ljiljana, Rajović Milica, Novaković Marijan, Miller Karolina, Binić Ivana, Vojvodić Danilo   +11 more
doaj   +1 more source

Use of Pegylated Interferon Alpha-2a in Cutaneous T-cell Lymphoma: A Retrospective Case Collection

Acta Dermato-Venereologica, 2023
Mycosis fungoides and Sézary syndrome are rare and largely incurable types of cutaneous T-cell lymphoma with limited therapeutic options. In 1984 Bunn et al.
Janika Gosmann, Rudolf Stadler, Koen D. Quint, Ralf Gutzmer, Maarten H. Vermeer   +4 more
doaj   +1 more source

Aspects of a Methodological Approach to Determination of Interferon Alpha Specific Activity

Биопрепараты: Профилактика, диагностика, лечение, 2020
Specific antiviral activity is one of the key indicators characterising pharmaceutical quality and pharmacological efficacy of interferon alpha products (IFN-α).
M. L. Baykova, I. M. Shcherbachenko, L. A. Gayderova, O. B. Ustinnikova, A. A. Movsesyants   +4 more
doaj   +1 more source

Anti-interferon alpha autoantibodies and their significance in COVID-19

Инфекция и иммунитет, 2022
During the last two years, treatment of patients with novel coronavirus infection COVID-19 remains an urgent health problem. Interferon proteins are known to play a significant role in antiviral immunity.
S. S. Petrikov, N. V. Borovkova, K. A. Popugaev, Mayya V. Storozheva, A. M. Kvasnikov, M. A. Godkov   +5 more
doaj   +1 more source

Recombinant alpha-2-interferon for hairy cell leukemia [PDF]

Blood, 1985
Twenty-two patients with hairy cell leukemia were treated with biosynthetic (recombinant) alpha-2-interferon in an open-label, single- arm efficacy study. Patients received 2 X 10(6) U/m2 recombinant alpha- 2-interferon three times weekly. Therapy was well tolerated subjectively with minimal short-term hematologic toxicity.
A D, Jacobs, R E, Champlin, D W, Golde
openaire   +3 more sources

Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies [PDF]

, 2013
PMCID: PMC3581439This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Trahtenherts, A Walker, Adam Walker, AM Wu, Armin Sepp, B Saunier, C. Andrew Boswell, CL Van Broekhoven, Clare Mudd, DJ Peng, DY Yang, E Dieperink, Edward Coulstock, ES Ward, F Pacifico, G Dusheiko, Gráinne Dunlevy, Jane Sosabowski, Jerome Burnet, JH Park, Julie Foster, KA Deal, Laura Goodall, LC Platanias, LJ Holt, LJ Holt, M Abe, M Loignon, M Spiess, Marie Davies, Milan Ovečka, MW Fried, MW Fried, P Kallinteri, R Duncan, R Gay, R Iorio, Rob Prince, T Eto, U Iyer, U Treichel, WM Pardridge, XQ Zhang, Y Zhang, YI Jeong, YY Seow   +45 more
core   +11 more sources

Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

Journal of Translational Medicine, 2008
Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro, Lonardi Silvia, Spinelli Elena, Chiarini Marco, Sottini Alessandra, Serana Federico, Facchetti Fabio, Ghidini Claudia, Badolato Raffaele, Caimi Luigi, Imberti Luisa   +10 more
doaj   +1 more source

Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]

, 2000
Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
Amann, B., Grunze, Heinz, Loeschke, K., Schlösser, S., Schmidt, F., Schäfer, Martin   +5 more
core   +1 more source