Results 31 to 40 of about 327,168 (302)
Intranasal interferon-alpha 2 for prevention of natural rhinovirus colds [PDF]
Antimicrobial Agents and Chemotherapy, 1984 The prophylactic activity of intranasal human interferon-alpha 2 (HuIFN-alpha 2) against natural rhinovirus colds was determined in a randomized, double-blind, placebo-controlled trial. A total of 304 working adults self-administered sprays of HuIFN-alpha 2 (10(7) IU/day) or a placebo once daily.
B M, Farr +3 more
openaire +2 more sources
Increased interferon alpha receptor 2 mRNA levels is associated with renal cell carcinoma metastasis
BMC Cancer, 2007 Background Interferon-α (IFN-α) is one of the central agents in immunotherapy for renal cell carcinoma (RCC) and binds to the IFN-α receptor (IFNAR). We investigated the role of IFNAR in RCC.
Yamanishi Tomonori +6 more
doaj +1 more source
Enhancement of vaccinia virus based oncolysis with histone deacetylase inhibitors [PDF]
, 2010 Histone deacetylase inhibitors (HDI) dampen cellular innate immune response by decreasing interferon production and have been shown to increase the growth of vesicular stomatitis virus and HSV.
Atkins, H +15 more
core +1 more source
FREQUENCY OF SIDE EFFECTS OF ANTIVIRUS THERAPY FOR CHRONIC VIRUS HEPATITIS IN CHILDHOOD
Педиатрическая фармакология, 2010 In pediatrics, the issue of using antivirus therapy for chronic virus hepatitis is not sufficiently studied, there is search for rational combinations, schemes, doses and length of treatment. The article demonstrates results of using a combined antivirus
S.V. Romanova +6 more
doaj +2 more sources
Indian Journal of Ophthalmology, 2016 Purpose: To study the efficacy of intravitreal interferon alpha-2b for endotoxin-induced uveitis. Materials and Methods: A total of 36 rabbits were randomly allocated to one of the three groups: (1) received interferon plus balanced-salt solution; (2 ...
Mehrdad Afarid +4 more
doaj +1 more source
Лечащий Врач, 2022 A prospective comparative controlled study included 100 patients with a confirmed diagnosis of COVID-19 coronavirus infection, randomized into two groups: the main group (MG) – 50 patients receiving interferon alpha-2b preparations, rectal suppositories ...
A. V. Mordyk +6 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Update of interferon use in acute simple bronchitis in children
Zdorovʹe Rebenka, 2018 Background. The main etiological factors of acute simple bronchitis in children are respiratory viruses, and therefore interferon preparations can be used in the treatment of these respiratory diseases.
A.E. Abaturov, N.M. Tokarieva
doaj +1 more source
Interferon Side Effects: When Somatization Betrays You - A Case Report [PDF]
, 2015 Neuropsychiatric symptoms are widely reported in association with both hepatitis C and IFNα treatment [1]its sequelae, and its treatment. In particular, interferon, a primary component of treatment for chronic hepatitis C, has been strongly associated ...
Domingues, V., França, M., Neves, S.
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