Results 41 to 50 of about 327,168 (302)

An expert consensus for the management of chronic hepatitis B in Asian Americans. [PDF]

, 2018
BACKGROUND: Hepatitis B virus (HBV) infection is common with major clinical consequences. In Asian Americans, the HBsAg carrier rate ranges from 2% to 16% which approximates the rates from their countries of origin.
Abbas, Abbas, Ahn, Beasley, Beasley, Bisceglie, Bogr, Brown, Buti, Centers for Disease Control, Chae, Chan, Chang, Chang, Chang, Chang, Chang, Chao, Chaung, Chen, Chen, Chen, Chen, Chi, Chien, Choe, Chu, Clemente, Della Corte, European Association for the Study of the Liver, Evans, Fang, Fattovich, Fontana, Fung, Gish, Hadziyannis, Halperin, Hann, Heathcote, Hongthanakorn, Hoofnagle, Hu, Huang, Hung, Hyun, Iino, Iloeje, Jeng, Keeffe, Kim, Komatsu, Konstantinou, Kowdley, Kuo, Kwong, Lai, Lai, Lai, Lai, Lampertico, Lau, Lau, Lee, Lee, Liang, Liaw, Liaw, Liaw, Liew, Lin, Lin, Lin, Liu, Liu, Liu, Lok, Lok, Lok, Loomba, MacLachlan, Manegold, Marcellin, Marcellin, Marcellin, Marcellin, Marcellin, Marcellin, Martin, Martin-Carbonero, Mast, McClune, McMahon, Mitchell, Monte, Murata, Mutimer, Nafa, Nguyen, Nguyen, Nikolopoulos, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Pan, Papatheodoridis, Park, Park, Park, Patterson, Perrillo, Perrillo, Pollack, Prati, Qiu, Reijnders, Sarin, Seto, Seto, Sherman, Shim, Shiraki, Sinatra, Sinn, Soriano, Stevens, Takano, Takayama, Takkenberg, Terrault, Thibault, Thio, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tong, Tse, Wang, Wedemeyer, Wei, Wen, Wiseman, Wursthorn, Xie, Xu, Yi, Yi, Yu, Yu, Yuen, Yuen, Yuen, Yuen, Yuen, Zhang, Zhang, Zhang, Zou   +173 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Viferon Suppositoria in Therapy of Relapsing Herpesvirus Infection in Women

Антибиотики и Химиотерапия, 2020
The therapeutic efficacy of Viferon, a recombinant human interferon alpha-2b (rectal suppositoria) was studied in the therapy of relapsing herpesvirus infection in women. The clinical efficacy of the drug was recorded in 90% of the patients. The analysis
A. N. Vasilyev, ZN. A. Kagramanova, V. V. Malinovskaya, V. V. Parfenov   +3 more
doaj  

Immunogenicity of inactivated coronavirus disease 2019 vaccines in patients with chronic hepatitis B undergoing antiviral therapy

Frontiers in Microbiology, 2022
ObjectivesTo investigate the effect and its mechanisms of different antiviral agents on the immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with chronic hepatitis B (CHB).MethodsA total of 125 patients ...
Wen-Xin Wang, Wen-Xin Wang, Rui Jia, Jin-Wen Song, Xiaoning Zhang, Shuang-Nan Zhou, Fu-Sheng Wang, Fu-Sheng Wang, Junliang Fu, Junliang Fu   +9 more
doaj   +1 more source

Long-term complete response of multiple lung metastases from renal cell carcinoma induced by combination therapy with interferon alpha and UFT: a case report [PDF]

, 1993
We report a case of long-term complete response of multiple lung metastases of renal cell carcinoma (RCC) by the combination therapy with interferon alpha (IFN alpha) and UFT.
吉田, 修, 寺地, 敏郎, 岡田, 裕作, 竹内, 秀雄   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Clinical outcomes of different therapeutic options for COVID-19 in two Chinese case cohorts: A propensity-score analysis

EClinicalMedicine, 2021
Background: The timing of administration of agents and use of combination treatments in COVID-19 remain unclear. We assessed the effectiveness of therapeutics in cohorts in Hong Kong SAR and Anhui, China.
Carlos K.H. Wong, Eric Y.F. Wan, Sihui Luo, Yu Ding, Eric H.Y. Lau, Ping Ling, Xiaowen Hu, Edward C.H. Lau, Jerry Wong, Xueying Zheng, Benjamin J. Cowling, Jianping Weng, Gabriel M. Leung   +12 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Chickenpox in Children: Features of Treatment

Zdorovʹe Rebenka, 2014
We observed 96 children with chickenpox aged from 2 weeks to 17 years. These patients had violations of interferon and cytokine status. Inclusion of Laferobionum into complex of treatment for chickenpox in children contributes to a more rapid involution ...
S.A. Kramarev, O.V. Vygovskaya, V.V. Deyev, A.P. Moshich, O.F. Melnikov, A.V. Shashkina, Yu.Ye. Nadvorskaya, O.S. Pilipenko, T.A. Kolinko, U. Godvin   +9 more
doaj   +1 more source

Omalizumab may protect allergic patients against COVID-19: A systematic review

World Allergy Organization Journal, 2023
Omalizumab, which downregulates the immunoglobulin E (IgE) receptor site on plasmacytoid dendritic cells and thereby increases interferon-α (INF-α) production, may shorten the duration of viral infections by enhancing the antiviral immunity.A systematic ...
Daniele Giovanni Ghiglioni, MD, ET Laura Cozzi, MD, Riccardo Castagnoli, MD, PhD, Gaia Bruschi, MD, Laura Maffeis, MD, Paola Giovanna Marchisio, MD, Gian Luigi Marseglia, MD, Amelia Licari, MD, PhD   +7 more
doaj   +1 more source