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Interferon-gamma in leishmaniasis. [PDF]

open access: yesFrontiers in Immunology, 2013
Leishmaniasis is a complex disease that is caused by parasites of the Leishmania genus. Leishmania are further classified into several complexes, each of which can engage in distinct interactions with mammalian hosts resulting in differing disease ...
Peter Epeh Kima, Lynn eSoong
doaj   +4 more sources

Interferon-Gamma-Mediated Osteoimmunology [PDF]

open access: yesFrontiers in Immunology, 2018
Osteoimmunology is the interdiscipline that focuses on the relationship between the skeletal and immune systems. They are interconnected by shared signal pathways and cytokines.
Mengjia Tang   +3 more
doaj   +4 more sources

Interferon gamma in cancer immunotherapy

open access: yesCancer Medicine, 2018
Immune system can recognize self vs transformed self. That is why cancer immunotherapy achieves notable benefits in a wide variety of cancers. Recently, several papers reported that immune checkpoint blockade therapy led to upregulation of IFNγ and in ...
Ling Ni, Jian Lu
doaj   +2 more sources

Interferon-Gamma Release Assays versus Tuberculin Skin Testing for the Diagnosis of Latent Tuberculosis Infection: An Overview of the Evidence

open access: yesPulmonary Medicine, 2013
A profusion of articles have been published on the accuracy and uses of interferon-gamma releasing assays. Here we review the clinical applications, advantages, and limitations of the tuberculin skin test and interferon-gamma release assays and provide ...
A. Trajman, R. E. Steffen, D. Menzies
doaj   +2 more sources

IFN-γ and TNF-α synergize to inhibit CTGF expression in human lung endothelial cells. [PDF]

open access: yes, 2012
Connective tissue growth factor (CTGF/CCN2) is an angiogenetic and profibrotic factor, acting downstream of TGF-β, involved in both airway- and vascular remodeling.
Fehrholz, Markus   +6 more
core   +24 more sources

Interferon-gamma inhibits influenza A virus cellular attachment by reducing sialic acid cluster size

open access: yesiScience, 2022
Summary: The mucosal antiviral role of type I and III interferon in influenza virus infection is well established. However, much less is known about the antiviral mechanism of type II interferon (interferon-gamma).
Carol Ho-Yan Fong   +7 more
doaj   +1 more source

Molecular characterization of the 3'-UTRsequence of the interferon-gamma gene and its expression profile in the ocular conjunctiva of amazon buffaloes [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2023
Interferon-gamma is an important innate immunomodulatory inflammatory cytokine, whose molecular characterization can demonstrate how this gene may or may not be conserved in populations throughout the evolutionary process.
Laura J. Paredes   +8 more
doaj   +1 more source

Novel approach to activity evaluation for release-active forms of anti-interferon-gamma antibodies based on enzyme-linked immunoassay. [PDF]

open access: yesPLoS ONE, 2014
Selection of a suitable assay to measure the activity of drug agents based on release-active forms of anti-interferon-gamma antibodies (RA forms of Abs) is an important step forward in the investigation of such agents.
Elena S Gavrilova   +5 more
doaj   +1 more source

Interferon-γ Inhibits Ebola Virus Infection. [PDF]

open access: yesPLoS Pathogens, 2015
Ebola virus outbreaks, such as the 2014 Makona epidemic in West Africa, are episodic and deadly. Filovirus antivirals are currently not clinically available.
Bethany A Rhein   +11 more
doaj   +1 more source

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