Results 231 to 240 of about 128,935 (252)

Polymorphisms of interferon‐γ and interferon‐γ receptor 1 genes and pulmonary tuberculosis in Koreans

Respirology, 2007
Background and objective:  Many genetic variations are thought to be risk factors for the development of pulmonary tuberculosis (TB). The association of interferon‐γ (IFN‐γ) and IFN‐γ receptor 1 (IFN‐γR1) gene polymorphisms with pulmonary TB is controversial. This study examined the association between IFN‐γ and IFN‐γR1 gene polymorphisms and pulmonary
Jung Hye, Hwang, Eun Joo, Kim, Su Yeon, Kim, Shin-Hye, Lee, Gee Young, Suh, O Jung, Kwon, Yongick, Ji, Miyeon, Kang, Duk-Hwan, Kim, Won-Jung, Koh   +9 more
openaire   +2 more sources

Purification of Interferon γ-Interferon γ Receptor Complexes by Preparative Electrophoresis on Native Gels

Analytical Biochemistry, 1993
Cytokine-receptor complexes are required for certain studies including crystallization, NMR spectra, and investigation of the biological response mechanism to the cytokine. The purity of the ligand-receptor complex is critical for most of these applications.
M, Fountoulakis, E, Takacs-di Lorenzo, J F, Juranville, M, Manneberg   +3 more
openaire   +2 more sources

Specific membrane receptors for human interferon-gamma (IFN-gamma).

Behring Institute Mitteilungen, 1987
IFN-gamma is a T-cell derived lymphokine which possesses antitumoral activity for a variety of malignant cells by virtue of its direct effect on cell growth and by its immunomodulatory activity. All IFN-gamma actions are initiated by binding to high affinity cell surface receptors, which are constitutively expressed in virtually all cell lines from ...
U, Ucer, P, Scheurich, H, Bartsch, D, Berkovic, C, Ertel, K, Pfizenmaier   +5 more
openaire   +1 more source

Increasing Affinity of Interferon-gamma Receptor 1 to Interferon-gamma by Computer-Aided Design

2013
We describe a computer-based protocol to design protein mutations increasing binding affinity between ligand and its receptor. The method was applied to mutate interferon-gamma receptor 1 (IFN-gamma-Rx) to increase its affinity to natural ligand IFN-gamma, protein important for innate immunity.
Mikulecký, P. (Pavel), Černý, J. (Jiří), Biedermannová, L. (Lada), Petroková, H. (Hana), Kuchař, M. (Milan), Vondrášek, J. (Jiří), Malý, P. (Petr), Šebo, P. (Peter), Schneider, B. (Bohdan)   +8 more
openaire   +1 more source

Lack of interferon gamma receptor beta chain and the prevention of interferon gamma signaling in TH1 cells.

Science (New York, N.Y.), 1995
The ability of interferon gamma (IFN-gamma) to inhibit the proliferation of type 2 T helper cells (TH2), but not that of type 1 (TH1) cells, suggests that helper cell subsets might differ in their activation of the IFN-gamma signaling pathway. The IFN-gamma-inducible signal transducing factor (STF-IFN gamma) was activated in murine TH2 but not in TH1 ...
A, Pernis, S, Gupta, K J, Gollob, E, Garfein, R L, Coffman, C, Schindler, P, Rothman   +6 more
openaire   +1 more source

T-Cell Mineralocorticoid Receptor Controls Blood Pressure by Regulating Interferon-Gamma

Circulation Research, 2017
Xue-Nan Sun, Chao Li, Mingjiang Zhu
exaly  

Serum Levels of Interferon-gamma, Cytotoxic Factor and Soluble Interleukin-2 Receptor in Childhood Hemophagocytic Syndromes

Leukemia and Lymphoma, 1991
Shinsaku Imashuku, Satoshi Ikushima, Noriko Esumi   +2 more
exaly  

The course of Plasmodium chabaudi chabaudi infections in interferon‐gamma receptor deficient mice

Parasite Immunology, 1997
N Favre, Bernhard Ryffel, W Rüdin
exaly  

Molecular characterization of novel interferon gamma receptor 1 isoforms in zebrafish (Danio rerio) and goldfish (Carassius auratus L.)

Molecular Immunology, 2009
Leon Grayfer, Miodrag Belosevic
exaly  

INCREASED EXPRESSION OF INTERFERON (IFN)-GAMMA TOGETHER WITH IFN-GAMMA RECEPTOR IN THE RHEUMATOID SYNOVIAL MEMBRANE COMPARED WITH SYNOVIUM OF PATIENTS WITH OSTEOARTHRITIS

Rheumatology, 1996
Radboud J E M Dolhain, Marc De Ley, E Claassen   +2 more
exaly