Results 251 to 260 of about 201,455 (289)
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Interferon-Induced Sarcoidosis
JCR: Journal of Clinical Rheumatology, 2006Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis.
Mittie K, Doyle +2 more
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Interferon-Induced Sarcoidosis
Journal of Computer Assisted Tomography, 2003Interferons have been used as therapy of both malignant and nonmalignant diseases and commonly in the treatment of hepatitis C virus infection. Although the most commonly encountered side effects of interferon therapy include nonspecific constitutional symptoms, pulmonary involvement is rare.
Ami N, Rubinowitz +2 more
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Interferons and Interferon Inducers
JAMA: The Journal of the American Medical Association, 1973The fascinating field of the interferons is thoroughly reviewed and brought up to date in this fine volume in the series, Frontiers of Biology . Though a multiauthored presentation, it contains surprisingly little redundancy, a compliment to the editor, N. B. Finter.
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Interferons and interferon-induced antiviral proteins in the testis
Journal of Reproductive Immunology, 1998Despite the dramatic development of sexually transmissible diseases, the antiviral capabilities of testicular cells have not yet been explored. Interferons (IFNs) are proteins playing a key role in the antiviral defense system, their activity being mediated by several IFN-induced proteins.
N, Dejucq, M O, Liénard, B, Jégou
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Interferons and Interferon Inducers
Drugs, 1982Interferons are broadly antiviral, naturally occurring substances, whose exact mechanism of action on virus infections is unknown. Major limitations on the quantities of interferon available for clinical trials have inhibited its development as a therapeutic agent. The variable nature of virus infections in certain patient populations has also produced
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2007
4. Structural Requirements for Interferon Induction by Synthetic Interferon Inducers . . . . . . . . . . . . . . . . . 183 4.1. Polycarboxylates . . . . . . . . . . . . . . . . 183 4.2. Polynucleotides . . . . . . . . . . . . . . . . . 184 4.2.1. Sufficiently High Molecular Weight . . . . . . . . 184 4.2.2. Stable, Highly Ordered Secondary Structure . .
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4. Structural Requirements for Interferon Induction by Synthetic Interferon Inducers . . . . . . . . . . . . . . . . . 183 4.1. Polycarboxylates . . . . . . . . . . . . . . . . 183 4.2. Polynucleotides . . . . . . . . . . . . . . . . . 184 4.2.1. Sufficiently High Molecular Weight . . . . . . . . 184 4.2.2. Stable, Highly Ordered Secondary Structure . .
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Induction of interferons and interferon-induced genes
Biotherapy, 1996Type I IFNs (IFN-α, IFN-β, and IFN-ω) are produced in most cell types upon virus infection and upon stimulation by dsRNA (with exceptions of embryonal carcinoma cells which are defective in expressing IFN genes). In addition, certain growth factors and lymphokines such as IL-1, colony stimulating factor (CSF), and TNF also induce type I IFNs.
Charles E. Samuel, Keiko Ozato
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Macrophage Activation by Interferon or Interferon Inducers
1980There are at least three types of mechanism which singly or in combination may underlie macrophage activation by an administered agent: 1) the agent may directly affect macrophages or macrophage precursors; 2) the agent may trigger the complement, clotting, or plasminogen cascades to generate effector molecules which in turn affect the function of ...
M. Rabinovitch +3 more
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