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Radioprotective activity of interferon inducers

Archives of Virology, 1978
The radioprotective activity of interferon inducers (tilorone, Acranil, poly I:C and LPS) was investigated against acute X-ray irradiation and prolonged 60Co-gamma rays irradiation. The endogenous spleen colony formation test and percentage of surviving mice 30 days after irradiation were used as indicators.
M, Tálas, E, Szolgay
exaly   +3 more sources

The Interferon-Inducible GTPases

Annual Review of Cell and Developmental Biology, 2006
Mammalian cells respond to interferons (IFNs) secreted during infection by the transcriptional upregulation of as many as a thousand genes. This remarkable transition prepares cells and organisms for resistance to infection, and many IFN-regulated gene products are players in well-understood resistance programs.
Martens, Sascha, Howard, Jonathan
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Interferon-Induced Sarcoidosis

Journal of Computer Assisted Tomography, 2003
Interferons have been used as therapy of both malignant and nonmalignant diseases and commonly in the treatment of hepatitis C virus infection. Although the most commonly encountered side effects of interferon therapy include nonspecific constitutional symptoms, pulmonary involvement is rare.
Ami N, Rubinowitz   +2 more
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Interferon-Induced Sarcoidosis

JCR: Journal of Clinical Rheumatology, 2006
Rheumatologists are increasingly asked to see patients with hepatitis C who exhibit a variety of clinical and serologic features that mimic systemic rheumatic disease. Treatment with interferons, now the standard of care, can precipitate a variety of inflammatory conditions, including sarcoidosis.
Mittie K, Doyle   +2 more
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