Results 11 to 20 of about 80,233 (311)
Journal of Indian Academy of Oral Medicine and Radiology, 2005 Interferons are a family of proteins and glycoproteins that have a variety of biologic actions. Interferons were first discovered in 1957 and several clinical trials have been conducted since then to unravel the action and clinical applications of ...
Karthikeya Patil +2 more
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Immunoregulatory Mechanisms of Interferon [PDF]
, 2020 Interferons (IFN) belong to the family of cytokines and have been described first in the late 1950s as an inhibitory factor of viral replication. Since then, the impact of interferon has been greatly expanded and its function comprises a role not only in
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Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. [PDF]
, 2010 Specific differences in signaling and antiviral properties between the different Lambda-interferons, a novel group of interferons composed of IL-28A, IL-28B and IL-29, are currently unknown.
Ralf Bartenschlager +19 more
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Interferons in hematopoiesis and leukemia [PDF]
, 2013 Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis.
Ochsenbein, Adrian F. +2 more
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Intracellular interferons in fish : a unique means to combat viral infection [PDF]
, 2013 Peer ...
Pin Nie +28 more
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Mediators of Inflammation, 1994 The in vitro action of interferon (IFN)-α and IFN-γ from six healthy donors and ten patients with multiple sclerosis (MS) on natural killer (INK) activity of peripheral blood lymphocytes (PBL) was studied in an autologous system.
S. B. Cheknev +5 more
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TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice
Cell Reports, 2016 Despite their antiviral effect, the in vivo effect of interferons on HIV transmission is difficult to predict, because interferons also activate and recruit HIV-susceptible cells to sites of infection.
Lee Adam Wheeler +11 more
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Canadian Journal of Infectious Diseases, 1994 The role of interferons in the treatment of cancer continues to evolve. Despite limited single agent activity against solid tumours, interferons now appear to have an important role as modulators of the activity of a variety of cytotoxic drugs.
Scott Wadler
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Journal of Translational Medicine, 2018 Background Ovarian cancer has no definitive second line therapeutic options, and largely recurs in the peritoneal cavity. Locoregional immune therapy using both interferons and monocytes can be used as a novel approach.
Daniel S. Green +10 more
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The Roles of Amphibian (Xenopus laevis) Macrophages during Chronic Frog Virus 3 Infections
Viruses, 2021 Infections by Frog Virus 3 (FV3) and other ranavirus genus members are significantly contributing to global amphibian decline. The Xenopus laevis frog is an ideal research platform upon which to study the roles of distinct frog leukocyte populations ...
Muhammad Riadul Haque Hossainey +4 more
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