Results 71 to 80 of about 418,590 (365)
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
Interferon and Interferon Inducers in the Treatment of Malignancies [PDF]
Archives of Internal Medicine, 1970 Several laboratories have reported that viral interference, 1 interferon, 2 and interferon inducers 3,4 can inhibit the growth of oncogenic viruses in tissue culture, 5 and can alter the course of murine leukemias in animals. 6,7 It has also been shown that the double-stranded RNA, polyriboinosinic: polyribocytidylic acid (poly I:C), which among other ...
Hilton B. Levy +2 more
openaire +6 more sources
Journal of Indian Academy of Oral Medicine and Radiology, 2005 Interferons are a family of proteins and glycoproteins that have a variety of biologic actions. Interferons were first discovered in 1957 and several clinical trials have been conducted since then to unravel the action and clinical applications of ...
Karthikeya Patil +2 more
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Interferons in the treatment of myeloproliferative neoplasms
Therapeutic Advances in HematologyInterferons are cytokines with immunomodulatory properties and disease-modifying effects that have been used to treat myeloproliferative neoplasms (MPNs) for more than 35 years.
Pankit Vachhani +11 more
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Immunity, Inflammation and Disease, 2020 Introduction CD64 expression increases on neutrophils during bacterial infections. Recently an increase in CD169 expression has been discovered on monocytes during viral infections.
Pénélope Bourgoin +4 more
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Инфекция и иммунитет, 2020 A study was conducted to evaluate effectiveness of vitamin D and interferon α-2b preparations on cytokine profile in pregnant women with vaginal infections. It was shown that pregnant women with vs.
M. P. Kostinov +7 more
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Stimulator of Interferon Genes (STING) Triggers Adipocyte Autophagy
Cells, 2023 Innate immune signaling in adipocytes affects systemic metabolism. Cytosolic nucleic acid sensing has been recently shown to stimulate thermogenic adipocyte differentiation and protect from obesity; however, DNA efflux from adipocyte mitochondria is a ...
Kornél Z. Varga +8 more
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bioRxiv, 2018 It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on epithelial cells suggests functional differences at epithelial surfaces.
K. Pervolaraki +10 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source
Multiple sclerosis: evidence and controversies [PDF]
Revista Ciencias de la Salud, 2006 Introduction: Multiple sclerosis is a chronicrecurrent inflammatory disorder of the centralnervous system. The pharmacological treatmentof multiple sclerosis has been evaluated withmultiple controlled clinical trials that allow theclinician to count with
Ángela María Gutiérrez-Álvarez
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