Results 1 to 10 of about 1,122,542 (370)

Clinical Significance and Immunologic Landscape of a Five-IL(R)-Based Signature in Lung Adenocarcinoma

open access: yesFrontiers in Immunology, 2021
Interleukins (ILs) and interleukin receptors (ILRs) play important role in the antitumor immune response. However, the expression signature and clinical characteristics of the IL(R) family in lung adenocarcinoma (LUAD) remains unclear.
Tao Fan   +6 more
doaj   +1 more source

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

open access: yesmedRxiv, 2021
Background: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: We evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform ...
A. Gordon   +61 more
semanticscholar   +1 more source

Interleukin-6 and tumor necrosis factor-α levels in tear film of Keratoconus patients

open access: yesJournal of Research in Medical Sciences, 2021
Background: It is hypothesized that increased inflammatory markers in keratoconus (KC) may be one of the causes of corneal damage. The aim of our study was to the measurement of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL)-6 in tear of ...
Alireza Peyman   +5 more
doaj   +1 more source

Interleukin 30 to Interleukin 40 [PDF]

open access: yesJournal of Interferon & Cytokine Research, 2018
Cytokines are important molecules that regulate the ontogeny and function of the immune system. They are small secreted proteins usually produced upon activation of cells of the immune system, including lymphocytes and myeloid cells. Many cytokines have been described, and several have been recognized as pivotal players in immune responses and in human
Catalan-Dibene, Jovani   +2 more
openaire   +3 more sources

The Interleukins [PDF]

open access: yesPediatric Research, 1988
In this review we have summarized the large mass of information that has accumulated in recent years relative to the heterogeneous group of molecules known as the interleukins (IL), the lymphokines, and the cytokines that control the growth and differentiation of cells of the hematopoietic and lymphoid lineage and cells of other lineages. Our intent is
W, Strober, S P, James
openaire   +2 more sources

The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature

open access: yesFrontiers in Immunology, 2021
The level of immunoglobulins and cytokines changes with an ageing immune system. This review summarizes findings from studies that have examined the impact of acute and chronic exercise on immunoglobulins and cytokines in the elderly.
Maha Sellami   +4 more
doaj   +1 more source

Interleukin-16 [PDF]

open access: yesJournal of Leukocyte Biology, 1997
Abstract Interleukin 16 (IL-16) was initially described in 1982 as the first T cell chemoattractant. Through interaction with CD4, IL-16 has now been characterized as a chemoattractant for a variety of CD4+ immune cells. Recent in vivo studies have more fully characterized IL-16 as an immunom  odulatory cytokine that contributes to the ...
W W, Cruikshank   +2 more
openaire   +3 more sources

Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease

open access: yesCirculation Research, 2021
IL (interleukin)-6 is a pivotal cytokine of innate immunity, which enacts a broad set of physiological functions traditionally associated with host defense, immune cell regulation, proliferation, and differentiation.
P. Ridker, Manas Rane
semanticscholar   +1 more source

Interleukin signaling [PDF]

open access: yesCurrent Biology, 2002
International ...
Vosshenrich, Christian A. J.   +1 more
openaire   +5 more sources

Recovery of Diabetic Rats After Physical Exhaustion: Kinetic Alterations in Muscle Inflammation and Muscle-Signaling Proteins to Atrophy and Hypertrophy

open access: yesFrontiers in Physiology, 2020
The complexity of the adaptive response of diabetics to intense exercise is still poorly understood. To optimize exercise interventions in diabetics, the chronology of inflammatory mediators in muscle and the signaling involved in muscle hypertrophy ...
José Ricardo Bortolon   +6 more
doaj   +1 more source

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