Results 21 to 30 of about 30,833,634 (232)

cDNA Cloning of Biologically Active Chicken Interleukin-18 [PDF]

, 2000
By searching a chicken EST database, we identified a cDNA clone that appeared to contain the entire open reading frame (ORF) of chicken interleukin-18 (ChIL-18).
Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Baeuerle, Patrick A., Kaspers, Bernd, Kirsten Schneider, Schneider, Kirsten, Baeuerle, Daniela, Daniela Baeuerle, Kirsten C. Weining, Puehler, Florian, Elvers, Sandra, Weining, Kirsten C., Florian Puehler, Sandra Elvers, Bernd Kaspers   +15 more
core   +1 more source

Human mid-gestation amniotic fluid contains interleukin-16 bioactivity [PDF]

, 2009
CD4-positive cells are detectable in the human fetal gastrointestinal tract from 11 weeks of gestation. Interleukin-16 (IL-16) is a chemoattractant for CD4(+) cells and, via fetal swallowing of amniotic fluid, could mediate the influx of CD4(+) cells ...
Warner, J., John W. Holloway, Thornton, Catherine A., Diaper, Norma D., Holloway, John W., Diaper, N., Shute, Janis K., Warner, John O., Catherine A. Thornton, Janis K. Shute, John O. Warner, Holloway, J., Cathy Thornton, Holloway, Judith A., Shute, Jan, Norma D. Diaper, Thornton, C., Judith A. Holloway   +17 more
core   +1 more source

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes:the MRC-ILA Heart Study [PDF]

, 2014
AIMS: Acute coronary syndromes (ACSs) are driven by inflammation within coronary plaque. Interleukin-1 (IL-1) has an established role in atherogenesis and the vessel-response to injury. ACS patients have raised serum markers of inflammation.
Greenwood, J.P., Hall, Alistair S., Rothman, A.M.K., Morton, Allison C., Foley, C., Chase, A., Greenwood, John P, Chase, Alex, Morton, Allison C, Wang, Duolao, Rothman, Alexander M K, Banya, Winston, Clarke, B., Gunn, J., Crossman, David C, Rothman, Alexander M. K., Crossman, David C., Flather, Marcus D, Rothman, Alexander M.K., Clarke, Bernard, Fox, Keith, Fox, K., Banya, W., Hall, Alistair S, Gunn, Julian, Flather, Marcus D., Greenwood, John P., Foley, Claire, Hall, A.S., Morton, A.C.   +29 more
core   +1 more source

Pro-inflammatory interleukin-18 increases Alzheimer’s disease-associated amyloid-β production in human neuron-like cells [PDF]

, 2012
Background: Alzheimer’s disease (AD) involves increased accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles as well as neuronal loss in various regions of the neocortex.
Anderson, G., Anderson George, Ojala, J.O., Sutinen, E.M., Pirttilä Tuula, Antero Salminen, Salminen Antero, Johanna O Ojala, Salminen, A., Elina M Sutinen, George Anderson, Tuula Pirttilä, Pirttilä, T., Sutinen Elina M, Ojala Johanna O   +14 more
core   +2 more sources

Expression of Interleukin-1 and Interleukin-1 Receptors Type 1 and Type 2 in Hodgkin Lymphoma. [PDF]

PLoS ONE, 2015
Signaling through the IL-1-receptor type 1 (IL-1R1), IL-1 is required for initiation and maintenance of diverse activities of the immune system. A second receptor, IL-1R2, blocks IL-1 signal transduction. We studied expression of IL-1beta, IL-1R1, and IL-
Elisabeth Oelmann, Harald Stein, Wolfgang E Berdel, Hermann Herbst   +3 more
doaj   +1 more source

Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer

Frontiers in Pharmacology, 2017
Background: Mesenchymal stem cells (MSCs) and their chondrogenic differentiation have been extensively investigated in vitro as MSCs provide an attractive source besides chondrocytes for cartilage repair therapies.
Nicole Armbruster, Nicole Armbruster, Jennifer Krieg, Jennifer Krieg, Manuel Weißenberger, Carsten Scheller, Andre F. Steinert   +6 more
doaj   +1 more source

Interleukin‐1 Signaling on Vascular Smooth Muscle Cells Accelerates Atherosclerosis in a Murine Model of Kawasaki Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We previously showed that Lactobacillus casei cell wall extract‐induced Kawasaki disease (KD) vasculitis significantly accelerates atherosclerosis in hypercholesterolemic mice on high‐fat diet.
Shuang Chen, Asli Savas, Asli Atici, Youngho Lee, Malcolm Lane, Emily Aubuchon, Debbie Moreira, Alexander Hsu‐Wilbraham, Kenichi Shimada, Timothy R. Crother, Magali Noval Rivas, Moshe Arditi   +11 more
doaj   +1 more source

Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors

Journal of Neuroinflammation, 2011
Background We have previously outlined functional interactions, including feedback cycles, between several of the gene products implicated in the pathogenesis of Alzheimer's disease.
Liu Ling, Aboud Orwa, Jones Richard A, Mrak Robert E, Griffin W Sue T, Barger Steven W   +5 more
doaj   +1 more source

Hippocampal interleukin-33 mediates neuroinflammation-induced cognitive impairments

Journal of Neuroinflammation, 2020
Background Interleukin (IL)-33 is expressed in a healthy brain and plays a pivotal role in several neuropathologies, as protective or contributing to the development of cerebral diseases associated with cognitive impairments.
Flora Reverchon, Vidian de Concini, Vanessa Larrigaldie, Sulayman Benmerzoug, Sylvain Briault, Dieudonnée Togbé, Bernhard Ryffel, Valérie F. J. Quesniaux, Arnaud Menuet   +8 more
doaj   +1 more source

Involvement of Interleukin 1 Family in the Development of Inflammatory Response in the Infectious Process. 1. General Description of Interleukin 1 Family

Zdorovʹe Rebenka, 2014
The general characteristics of interleukin 1 family is given in the review.
A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish   +2 more
doaj   +1 more source