Results 71 to 80 of about 277,845 (282)

Effects of Treatment with Probiotics on Cognitive Function and Regulatory Role of Cortisol and IL-1β in Adolescent Patients with Major Depressive Disorder

Life, 2023
The aim of this study was to investigate the effects of probiotics on cognitive function and the regulation of cortisol and IL-1β in adolescents with depression.
Shaoli Shi, Shuyou Zhang, Lingming Kong
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]

, 2018
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core   +1 more source

Organochlorine pesticides exposure & preterm birth [PDF]

, 2016
Commento su invito ad uno studio su esposizione fetale a composti ...
Fuggetta, Eliana, Porpora, Maria Grazia, Resta, Serena   +2 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Interrelation of the dynamics of serum concentrations of interleukin-1β, interleukin-6 and interleukin-10 with clinical data in acute ischemic stroke and the strategy of reperfusion therapy

Бюллетень сибирской медицины, 2020
Aim. To study the relationship between the dynamics of serum concentrations of interleukin-1β, interleukin-6 and interleukin-10 with clinical data in the acute period of ischemic stroke, and the strategy of reperfusion therapy.Materials and methods.
A. Yu. Bykova, A. A. Kulesh, N. A. Kayleva, E. M. Kuklina, V. V. Shestakov   +4 more
doaj   +1 more source

Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes [PDF]

, 2016
BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders,
Cignarella, Andrea, Gaion, ROSA MARIA, Malorgio, Francesca, Nassi, Alberto, Tedesco, Serena   +4 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Interleukin-1β gene is not associated with preeclampsia in Taiwanese

Taiwanese Journal of Obstetrics & Gynecology, 2012
Objective: To identify associations between the interleukin-1β gene and preeclampsia in Taiwanese women. Methods and Materials: We genotyped Taiwanese population (102 women with preeclampsia and 148 controls) for two polymorphisms of the interleukin-1β ...
Lin Kang, Chung-Hwan Chen, Chen-Hsiang Yu, Chiung-Hsin Chang, Fong-Ming Chang   +4 more
doaj   +1 more source

Febrile seizures: mechanisms and relationship to epilepsy. [PDF]

, 2009
Studies of febrile seizures have been driven by two major enigmas: first, how these most common of human seizures are generated by fever has not been known.
Alheim, Amy L. Brewster, Annegers, Annegers, Aram, Audenaert, Balestrino, Ban, Baram, Baram, Barone, Bender, Bender, Berg, Berg, Berg, Berg, Berg, Brewster, Brewster, Cartmell, Cartmell, Cendes, Chang, Chen, Chen, Chen, Céline M. Dubé, Dubé, Dubé, Dubé, Dubé, Dzhala, Escayg, French, Fukuda, Gatti, Germano, Hamati-Haddad, Harkin, Haspolat, Heida, Heida, Holtzman, Ichiyama, Isaac, Jiang, Kamal, Kang, Lahat, Le Van Quyen, Lemmens, Morimoto, Morimoto, Moser, Nelson, Pellegrini-Giampietro, Provenzale, Racine, Raspall-Chaure, Richichi, Sanchez, Scantlebury, Schuchmann, Shibasaki, Shinnar, Stafstrom, Takao, Tallie Z. Baram, Tan, Theodore, Toth, Tütüncüoğlu, Verity, Verity, Verity, Vezzani, Virta, Wallace, Zerr   +79 more
core   +1 more source