Results 161 to 170 of about 24,572,041 (402)
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires+4 more
wiley +1 more source
Analysis of the salivary levels of immune biomarkers after inhalation of a steam mixed gas containing hydrogen gas [PDF]
スイソニアから発生する水素ガス(濃度0.1~0.3%)を含む蒸気混合ガス“XEN”を鼻カニューラで吸入した。吸入後、唾液中の免疫バイオマーカーの動態を酵素抗体法(enzyme immunoassay:EIA)で解析した。その結果、“XEN”吸入15分後、唾液中のインターロイキン-1β(IL-1β)の濃度が吸入前と比較して有意に増加した ...
Nobunao IKEWAKI+4 more
core
Aim. To enhance the efficiency of treatment in patients with secondary osteoarthritis (ОА) in the presence of comorbid condition, by using an interleukin-1 inhibitor (IL-1i) and laser therapy (LT). Subjects and methods. A total of 248 patients aged 38 to
I A Starodubtseva+2 more
doaj
The aim of the present study is to investigate the role of c-Jun N-terminal kinase (JNK) and matrix metalloproteinase-2 (MMP-2) in mediating the effects of interleukin-1β (IL-1β) on the function of lacrimal gland myoepithelial cells (MECs). MECs isolated
Junji Morokuma+5 more
doaj +1 more source
In vivo control of differentiation of myeloid leukemic cells by cyclosporine A and recombinant interleukin-1 alpha [PDF]
Joseph Lotem, Leo Sachs
openalex +1 more source
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim+12 more
wiley +1 more source
Gene polymorphisms in primary biliary cirrhosis: association with the disease and hepatic osteopathy [PDF]
Genetic factors have been implicated in the pathogenesis of osteoporosis, a common disorder in primary biliary cirrhosis (PBC). Estrogen receptor-alpha gene (ER- ), vitamin-D-receptor gene (VDR) and IL-1-receptor-antagonist gene (IL-1RN) are all ...
Bajnok, Éva+6 more
core
Modulation of adult hippocampal neurogenesis by interleukin 1 signaling
Adult hippocampal neurogenesis (AHN) plays a critical role in cognition and emotional regulation. Recent studies have linked compromised AHN to numerous neurological and psychological disorders.
Maria I. Smirnova, Ning Quan
doaj
Synthesis of Sterols and 5‐Lipoxygenase Products are Required for the G1‐S Phase Transition of Interleukin‐2‐Dependent Lymphocyte Proliferation [PDF]
Shingo Hata+5 more
openalex +1 more source
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray+2 more
wiley +1 more source