Results 171 to 180 of about 24,635,826 (402)
Advanced Functional Materials, EarlyView.A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song +8 more
wiley +1 more source
Frontiers in OphthalmologyThe aim of the present study is to investigate the role of c-Jun N-terminal kinase (JNK) and matrix metalloproteinase-2 (MMP-2) in mediating the effects of interleukin-1β (IL-1β) on the function of lacrimal gland myoepithelial cells (MECs). MECs isolated
Junji Morokuma +5 more
doaj +1 more source
Point mutations of human interleukin‐1 with decreased receptor binding affinity [PDF]
, 1986 H. Robson MacDonald +5 more
openalex +1 more source
High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles
Advanced Functional Materials, EarlyView.The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires +4 more
wiley +1 more source
International Journal of COPD, 2017 Katherine J Baines,1,2 Juan-juan Fu,3 Vanessa M McDonald,1,2 Peter G Gibson1,2 1Faculty of Health and Medicine, Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, 2Department of Respiratory and ...
Baines KJ, Fu JJ, McDonald VM, Gibson PG
doaj
Antigen presentation by EBV-B cells to resting and activated T cells: role of interleukin 1. [PDF]
, 1985 E T Chu +4 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Interleukin 1 production during accessory cell-dependent mitogenesis of T lymphocytes. [PDF]
, 1989 Nina Bhardwaj +4 more
openalex +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim +12 more
wiley +1 more source
Bradykinin stimulates tumor necrosis factor and interleukin‐1 release from macrophages [PDF]
, 1989 Carol W. Tiffany, Ronald M. Burch
openalex +1 more source