Results 211 to 220 of about 703,665 (265)
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Immunology Today, 1987
One of the pivotal events in the initiation of inflammatory responses is activation of both resident tissue macrophages at the site of damage and circulating monocytes infiltrating the area. The activated macrophages release a group of factors which influence inflammation and tissue regulation.
S K, Dower, D L, Urdal
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One of the pivotal events in the initiation of inflammatory responses is activation of both resident tissue macrophages at the site of damage and circulating monocytes infiltrating the area. The activated macrophages release a group of factors which influence inflammation and tissue regulation.
S K, Dower, D L, Urdal
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The FASEB Journal, 1988
Interleukin 1 (IL 1) is a polypeptide that is produced after infection, injury, or antigenic challenge. Although the macrophage is a primary source of IL 1, epidermal, epithelial, lymphoid, and vascular tissues synthesize IL 1.
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Interleukin 1 (IL 1) is a polypeptide that is produced after infection, injury, or antigenic challenge. Although the macrophage is a primary source of IL 1, epidermal, epithelial, lymphoid, and vascular tissues synthesize IL 1.
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Interleukin 1 alpha and an interleukin 1 beta fragment are somnogenic
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1990The somnogenic activity of interleukin 1 beta (IL-1 beta) has previously been established. Interleukin 1 alpha (IL-1 alpha) is a distinct gene product that possesses similar biological activities. We report here that IL-1 alpha, like IL-1 beta, has the capacity in rabbits to enhance non-rapid-eye-movement sleep, electroencephalographic slow-wave (0.5 ...
F, Obal +7 more
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The interleukin-1 receptor family
Seminars in Immunology, 2006The cytokines IL-1 and IL-18 are key molecules both in the innate and in the adaptive immune response. Their activity is mediated by specific receptors present on the membrane of target cells. It has become apparent that these receptors are members of a larger family of related receptors, most of which are apparently involved in the mechanisms of host ...
Boraschi D, Tagliabue A
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The family of the interleukin‐1 receptors
Immunological Reviews, 2017SummaryThe extracellular forms of the IL‐1 cytokines are active through binding to specific receptors on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand‐binding receptor chain. For signaling to take place, a non‐binding accessory chain is recruited into a heterotrimeric complex.
Boraschi +4 more
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Interleukin-1 and hematopoiesis
Blood Reviews, 1989Interleukin-1 alpha and interleukin-1 beta are 17.5 kDa peptides which exert a wide variety of biological activities. Both forms of interleukin bind to a common 60-70 kDa receptor expressed by most somatic cells. One major effect of interleukin-1 is to induce the expression of other genes, including genes for other interleukins (IL-6), colony ...
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Neuroendocrinology of Interleukin-1
1990Inflammatory processes and infectious diseases induce a constellation of host responses referred to as acute phase response (1,2). These responses include changes in immunologic, metabolic, neurologic, and endocrinologic functions. Although many of its components are far from being understood, it is generally believed that the acute phase response ...
F, Berkenbosch +3 more
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1995
Abstract The human type I IL-1 receptor is predicted from the cDNA sequence to be a protein of 569 amino acids (GenBank accession number M27492; mouse, M20658; rat, M95578; chicken, M81846) (Sims et al. 1989). It contains a 20-aminoacid signal peptide, an extracellular region of 317 amino acids, a single 22-amino-acid transmembrane ...
J E, Sims, S K, Dower
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Abstract The human type I IL-1 receptor is predicted from the cDNA sequence to be a protein of 569 amino acids (GenBank accession number M27492; mouse, M20658; rat, M95578; chicken, M81846) (Sims et al. 1989). It contains a 20-aminoacid signal peptide, an extracellular region of 317 amino acids, a single 22-amino-acid transmembrane ...
J E, Sims, S K, Dower
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2016
The interleukin-1 (IL-1) family consists of several pro- or anti-inflammatory proteins, with pro-inflammatory IL-1β being its best characterized member. IL-1β is one of the most prominent mediators of inflammation resulting in fever and immune activation via binding to IL-1 receptor 1. Due to its potency, its secretion is tightly regulated.
Amir S, Yazdi, Kamran, Ghoreschi
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The interleukin-1 (IL-1) family consists of several pro- or anti-inflammatory proteins, with pro-inflammatory IL-1β being its best characterized member. IL-1β is one of the most prominent mediators of inflammation resulting in fever and immune activation via binding to IL-1 receptor 1. Due to its potency, its secretion is tightly regulated.
Amir S, Yazdi, Kamran, Ghoreschi
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Interleukin‐1 in reproductive strategies
Evolution & Development, 2008SUMMARY Evolutionary studies on different classes of vertebrates could help clarify the role of cytokines in acceptance of the embryo by the maternal tissues. This review focuses on the cytokine interleukin‐1 (IL‐1) and reports on its presence in the female reproductive tract of species with different reproductive strategies, that is, viviparity,
Ricci, Luana +4 more
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