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Interferons as inhibitors of interleukin 1 induced interleukin 1 synthesis.
Lymphokine research, 1989IL-1 induces its own gene expression in cultured smooth muscle and endothelial cells and in human PBMC. IL-1-induced IL-1 may be part of a self-amplification or autocrine event in inflammation. In the present study IFN gamma consistently increased LPS-induced IL-1, but reduced the total amount of IL-1-induced IL-1 from PBMC. On a molar basis, IFN gamma
Schindler, R, Ghezzi, P, Dinarello, C A
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The interleukin-1/interleukin-1-receptor interaction
Annales de l'Institut Pasteur / Immunologie, 1987H R, MacDonald, J W, Lowenthal
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Interleukin-1 and interleukin-1 receptor antagonist.
Nutrition (Burbank, Los Angeles County, Calif.), 1996Cytokines are produced in disease or during immunologic challenge. Some cytokines increase host resistance to disease whereas others trigger inflammatory processes. Interleukin 1 (IL-1) and tumor necrosis factor (TNF) are pro-inflammatory cytokines that affect nearly every cell either alone or in a synergistic fashion.
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Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
Circulation Research, 2021exaly
Interleukin-1 and Endometriosis
Fertility and Sterility, 1987Paul G. McDonough +2 more
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Induction of interleukin-1 and interleukin-1 receptor antagonist.
Seminars in oncology, 1997Drugs that affect the production or action, or both, of the pleiotropic inflammatory cytokine interleukin-1 (IL-1) are predicted to have a significant impact on a variety of human diseases. The biochemical properties of IL-1 and the IL-1 receptor antagonist, the mechanism for their production, and the factors that regulate their release are discussed ...
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Biology and therapeutic potential of interleukin-10
Journal of Experimental Medicine, 2020Anne O'Garra +2 more
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Interleukin-22: Immunobiology and Pathology
Annual Review of Immunology, 2015Jarrod Dudakov, Alan Hanash
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