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The interleukin-10 family of cytokines

Trends in Immunology, 2002
A family of interleukin-10 (IL-10)-related cytokines has emerged, comprising a series of herpesviral and poxviral members and several cellular sequence paralogs, including IL-19, IL-20, IL-22 [IL-10-related T-cell-derived inducible factor (IL-TIF)], IL-24 [melanoma differentiation-associated antigen 7 (MDA-7)] and IL-26 (AK155).
Helmut, Fickenscher   +5 more
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Biological properties of interleukin 10

Journal of Clinical Immunology, 1992
Interleukin 10 (IL-10) was discovered in 1989 by Mosmann and colleagues as an activity produced by murine type 2 helper T cells which suppressed cytokine production by type 1 helper T cells (1). This activity, initially designated cytokine synthesis inhibitor factor (CSIF), was isolated by expression cloning by Moore and colleagues (2), who ...
M, Howard   +4 more
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Regulation of Interleukin-10 Expression

2016
Interleukin (IL)-10 is an essential anti-inflammatory cytokine that plays important roles as a negative regulator of immune responses to microbial antigens. Loss of IL-10 results in the spontaneous development of inflammatory bowel disease as a consequence of an excessive immune response to the gut microbiota.
Sascha, Rutz, Wenjun, Ouyang
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Interleukin 10

Cytokine, 1991
A, Zlotnik, K W, Moore
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Interleukin-10 and Cancer

Cancer Investigation, 1993
G, Holland, A, Zlotnik
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Interleukin-10 and interleukin-10 receptor in human osteoarthritic and healthy chondrocytes.

Clinical and experimental rheumatology, 2001
To evaluate the expression of interleukin-10 (IL-10) and interleukin-10 receptor (IL-10R) on chondrocytes from healthy, osteoarthritic, and foetal cartilage from human subjects.Articular cartilage was obtained from 12 patients with osteoarthritis (OA) undergoing surgical knee replacement.
Iannone, F   +7 more
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Interleukin-10

1999
info:eu-repo/semantics ...
Pretolani, M.   +2 more
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Interleukin-10 (IL-10)

1995
In the 5 years since its discovery, the pleiotropic cytokine IL-10 has been shown to play an important role in the regulation of lymphoid and myeloid cells. IL-10 was detected independently in several laboratories. Fiorentino et al. [1] described a cytokine secreted by ‘type 2’ murine helper T-cell clones which inhibited cytokine production by ‘type 1’
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Interleukin-10 and Transplantation Tolerance

1995
Despite significant progress in the past 20 years, induction of tolerance to host and donor HLA antigens after allogeneic transplantation, remains a rare event. Graft rejection and graft-versus-host disease (GVHD) are still the major obstacles to reach long-term engraftment and disease-free survival in patients transplanted with allogeneic ...
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