Results 221 to 230 of about 7,946,940 (284)

A Diagnostic Challenge: A Case of Disseminated Nocardiosis Presenting With Generalized Lymphadenopathy in a Patient With Interleukin-12 Deficiency. [PDF]

Cureus
Mitwalli H, Alekrish Y, Nafisah F, Alkhamshi A.   +3 more
europepmc   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

Effects of fermentation conditions (salt concentration, temperature, and pH) on Lactobacillus strains for induction of interleukin-12 in the exposed murine splenocytes. [PDF]

Heliyon
Hadinia N, Yavarmanesh M, Edalatian Dovom MR.   +2 more
europepmc   +1 more source

Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery

Advanced Science, EarlyView.
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie, Jiahe Liu, Xiangyu Zhao, Siying Yang, Han Sun, Bingqian Jia, Xiaohong Ren, Xintao Chen, Lixin Sun, Li Wu, Caifen Wang, Jiwen Zhang   +11 more
wiley   +1 more source

Evaluating the role of interleukin-2 and interleukin-12 in pediatric patients with concurrent Mycoplasma pneumoniae and Epstein-Barr virus infections. [PDF]

World J Clin Cases
Hao YP.
europepmc   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

Tumor-Localized Interleukin-2 and Interleukin-12 Combine with Radiation Therapy to Safely Potentiate Regression of Advanced Malignant Melanoma in Pet Dogs. [PDF]

Clin Cancer Res
Stinson JA, Barbosa MMP, Sheen A, Momin N, Fink E, Hampel J, Selting KA, Kamerer RL, Bailey KL, Wittrup KD, Fan TM.   +10 more
europepmc   +1 more source

Antitumor properties of traditional lactic acid bacteria: Short-chain fatty acid production and interleukin 12 induction. [PDF]

Heliyon
Mobasherpour P, Yavarmanesh M, Edalatian Dovom MR.   +2 more
europepmc   +1 more source

Oncolytic varicella-zoster virus engineered with ORF8 deletion and armed with drug-controllable interleukin-12. [PDF]

J Immunother Cancer
Jiang H, Nace R, Carrasco TF, Zhang L, Whye Peng K, Russell SJ.   +5 more
europepmc   +1 more source

Serum Levels of IL-35, One of the Newest Members of Interleukin-12 Family of Cytokines, in Patients With Vitiligo. [PDF]

Dermatol Pract Concept
Hayran Y, Yücel Ç, Oğuz EF, Eren F, Turhan T, Yalçın B.   +5 more
europepmc   +1 more source