Results 91 to 100 of about 576,830 (304)

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

Effect of 1,25-dihydroxy vitamin D3 on expression of pro-inflammatory cytokines in type Ⅱ innate lymphoid cells in

open access: yesDi-san junyi daxue xuebao, 2019
Objective To investigate the effect of 1,25-dihydroxy vitamin D3 [1,25-(OH)2-D3] on the expression of pro-inflammatory cytokines in type Ⅱ innate lymphoid cells (ILC2s) in asthmatic mice.
LI Chengcheng, WU Yi
doaj   +1 more source

IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. [PDF]

open access: yes, 2013
Type 2 immune responses are essential in protection against intestinal helminth infections. In this study we show that IL-22, a cytokine important in defence against bacterial infections in the intestinal tract, is also a critical mediator of anti ...
A Andoh   +48 more
core   +3 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Ферментативные активности сыворотки крови для диагностики и дифференциальной диагностики хронических диффузных заболеваний печени [PDF]

open access: yes, 2019
ГЕПАТИТ ХРОНИЧЕСКИЙ /ДИАГНКРИПТОГЕННЫЙ ХРОНИЧЕСКИЙ ГЕПАТИТ /ДИАГНЦИРРОЗЫ ПЕЧЕНИ /ДИАГНФИБРОЗ ПЕЧЕНИ /ДИАГНГИАЛУРОНИДАЗНАЯ АКТИВНОСТЬТРИПСИНОПОДОБНАЯ АКТИВНОСТЬДЕЗОКСИРИБОНУКЛЕАЗНАЯ АКТИВНОСТЬЭЛАСТАЗНАЯ АКТИВНОСТЬДифференциальная диагностика хронического ...
Прищепенко, В. А.
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Tilivalline- and Tilimycin-Independent Effects of Klebsiella oxytoca on Tight Junction-Mediated Intestinal Barrier Impairment [PDF]

open access: yes, 2019
Klebsiella oxytoca causes antibiotic-associated hemorrhagic colitis and diarrhea. This was attributed largely to its secreted cytotoxins tilivalline and tilimycin, inductors of epithelial apoptosis.
Bücker, Roland   +8 more
core   +1 more source

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