Results 111 to 120 of about 68,936,161 (293)

Clinical therapeutic effects of multi-target treatment on type-Ⅳ lupus nephritis and the effects on serum IL-6,IL-13,and IL-18 levels

open access: yesLinchuang shenzangbing zazhi, 2016
Objective To investigate the clinical therapeutic effects of multi-target inductive treatment on type-Ⅳ lupus nephritis(LN) and the effects on serum interleukin-6(IL-6),IL-13,and IL-18 levels.Methods A total of 60 eligible patients with LN of Department ...
ZHANG Yong   +3 more
doaj  

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks   +8 more
wiley   +1 more source

Cholinergic Urticaria, an Effective and Safe “Off Label” Use of Dupilumab: A Case Report with Literature Review

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Maria Maddalena Sirufo,1,2 Alessandra Catalogna,1,2 Martina Raggiunti,1,2 Francesca De Pietro,1,2 Lia Ginaldi,1,2 Massimo De Martinis1,2 1Department of Life, Health and Environmental Sciences, University of L’Aquila, L’Aquila, Italy; 2Allergology and ...
Sirufo MM   +5 more
doaj  

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu   +9 more
wiley   +1 more source

Exploration of novel therapeutic targets for keloids based on clinical and molecular data: the role of the IL-4/IL-13 signaling pathway

open access: yesEuropean Journal of Medical Research
Background and Objectives Keloids are problematic fibrotic lesions with excessive collagen and chronic inflammation; their underlying causes are not fully understood.
Xueli Li   +5 more
doaj   +1 more source

Receptor for Interleukin 13 [PDF]

open access: yesJournal of Biological Chemistry, 1995
Nicholas I. Obiri   +3 more
openaire   +2 more sources

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato   +27 more
wiley   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

open access: yesArthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy