Results 31 to 40 of about 3,870,583 (322)
Interaction of Interleukin-17A with a Th2 Response in a Mouse Model of Allergic Airway Inflammation
Cells, 2023 Background: A total of 262 million people worldwide suffer from asthma and 461000 people died from it in 2019. Asthma is a disease with different endotypes defined by the granulocytes found in the asthmatic lung.
Karin Peters +2 more
doaj +1 more source
JAMA dermatology, 2020 This phase 2b, placebo-controlled, randomized clinical trial evaluates the efficacy and safety of lebrikizumab, a novel, high-affinity, monoclonal antibody targeting interleukin (IL)–13 that selectively prevents formation of the IL-13Rα1/IL-4Rα ...
E. Guttman‐Yassky +7 more
semanticscholar +1 more source
BMC Pregnancy and Childbirth, 2023 Background Preeclampsia is the main cause of preterm parturition and maternal–fetal complications. T helper 1 and T helper 2 cytokines balance is a requirement in normal pregnancy and aberrant in this immunologic balance, play an important role in the ...
Sara Parhoudeh +5 more
doaj +1 more source
Interleukin-13 (IL-13) Pathway [PDF]
Science's STKE, 2005 Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T H 2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). It is also produced by activated eosinophils.
Ann, Kelly-Welch +2 more
openaire +2 more sources
Exercising Immunity: Interleukin-13 Flexes Muscle [PDF]
Immunity, 2020 Endurance exercise drives physiological changes in the muscle to optimize performance. In a recent study in Science, Knudsen et al. report a role for the type 2 cytokine interleukin-13 in orchestrating metabolic reprogramming that drives adaptation to endurance exercise.
Lauren M, Webb, Elia D, Tait Wojno
openaire +2 more sources
Cytokine profile associated with human chronic schistosomiasis mansoni
Memorias do Instituto Oswaldo Cruz, 2004 This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients.
Andréa Magalhães +9 more
doaj +1 more source
Decreased Expression of Leptin among Patients with Shoulder Stiffness
Life, 2022 Shoulder stiffness (SS) is a disease that is fibroblastic and inflammatory in nature. Leptin is an adipokine-mediating the fibroblastic and inflammatory processes of various diseases.
Jih-Yang Ko +5 more
doaj +1 more source
Interleukin-4 receptor alpha gene variants and allergic disease
Respiratory Research, 2000 The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to the risk of developing asthma in a given individual.
Hall Ian P
doaj +1 more source
Jurnal Respirasi, 2021 Asthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly ...
Resti Yudhawati +1 more
doaj +1 more source
Interleukin-25 Mediated Induction of Angiogenin-4 Is Interleukin-13 Dependent. [PDF]
PLoS ONE, 2016 The intestinal surface is directly exposed to both commensal microorganisms as well as pathogens with a single layer of epithelium separating luminal microorganisms from internal tissues.
Zannatun Noor +3 more
doaj +1 more source