Results 101 to 110 of about 3,298,250 (374)
Consilium MedicumAim. To evaluate the clinical efficacy and safety of netakimab (an interleukin-17 inhibitor) in hospitalized patients with severe COVID-19. Materials and methods. A retrospective case-control study was conducted involving 171 patients. The main group (
Zamira M. Merzhoeva +7 more
doaj +1 more source
Autoimmunity, 2018 A characteristic feature of primary Sjögren’s syndrome (pSS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration.
Lara A. Aqrawi +8 more
doaj +1 more source
Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis
BMC Medical Genomics, 2023 Background The pathogenesis of rheumatoid arthritis (RA) is an immune imbalance, in which various inflammatory immune cells and pro-inflammatory factors are involved.
Rong Zhao +7 more
doaj +1 more source
PLoS ONE, 2019 Introduction New generation biologics, including interleukin (IL)-17 and IL-23 inhibitors, have delivered higher rates of skin clearance than older treatments in head-to-head studies. However, studies comparing these new biologics directly to one another
L. Sawyer +7 more
semanticscholar +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]
, 2019 Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Breaban, Iulia +10 more
core +1 more source
Perivascular adipose tissue inflammation in vascular disease [PDF]
, 2017 Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core +1 more source
The role of interleukin-17 in tumor development and progression
Journal of Experimental Medicine, 2019 This review discusses the growing literature on the pathogenic role of IL-17 in cancer, focusing on recent studies that place IL-17 as a nexus linking inflammation, tissue repair, and cancer.
Junjie Zhao +3 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen +6 more
wiley +1 more source
Investigating the Effect of Endurance Training on Tumor Level of IL-8 and Serum Level of IL-17 in Female Mice with Breast Cancer [PDF]
Journal of Fasa University of Medical Sciences, 2015 Background & Objectives: Breast cancer is nowadays one of the most harmful threats to women’s health. However, exercise training plays an adjuvant role in breast cancer (Adjuvant also means preventive. So, no need to repeat preventing.). Therefore,
AR Kazemi +6 more
doaj +1 more source