Results 41 to 50 of about 3,298,250 (374)
Journal of Experimental Medicine, 2020 IL17 cross-talk with pancreatic cancer cells orchestrates neutrophil recruitment and activation of Padi4-dependent NETosis, resulting in immune spatial remodeling and immunosuppression reversal.
Yu Zhang +21 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2021 ObjectiveOsteoporosis is a common metabolic bone disease mainly involving bone remodeling and blood vessels. The current study aimed to explore the suppressive role of interleukin (IL)-35 in nuclear factor kappa-B ligand receptor activator (RANKL) and ...
Hui Zhang +7 more
doaj +1 more source
Interleukin-17 is required for control of chronic lung infection caused by Pseudomonas aeruginosa [PDF]
, 2016 Chronic pulmonary infection with Pseudomonas aeruginosa is a feature of cystic fibrosis (CF) and other chronic lung diseases. Cytokines of the IL-17 family have been proposed as important in the host response to P. aeruginosa infection through augmenting
Bayes, Hannah K. +2 more
core +1 more source
The Saudi Journal of Gastroenterology, 2018 Background/Aim: We studied the expression of interleukin-17 and interleukin-22 in the serum and the lower esophageal sphincter (LES) in healthy individuals and in patients diagnosed with achalasia (AC) to gain a better understanding of the ...
Zeyu Wang +4 more
doaj +1 more source
BMC Rheumatology, 2020 Background Osteoarthritis (OA) is a progressive, chronic disease characterized by articular cartilage destruction. The pro-inflammatory cytokine IL-17 levels have been reported elevated in serum and synovial fluid of OA patients and correlated with ...
Dovile Sinkeviciute +4 more
doaj +1 more source
Targeting interleukin-17 receptors
Oncotarget, 2015 During the last decade, increasing evidence suggests a strong association between chronic inflammation and cancer development among different types of cancer. The dysregulation of pro-inflammatory cytokines or their receptors is a common feature observed in many cancers [1]. Cancer cells take advantage of cytokine or cytokine receptor overexpression to
Wen-Hwa, Lee +2 more
openaire +2 more sources
Paradoxical gastrointestinal effects of interleukin-17 blockers
Annals of the Rheumatic Diseases, 2020 Secukinumab, ixekizumab and brodalumab are monoclonal antibody therapies that inhibit interleukin (IL)-17 activity and are widely used for the treatment of psoriasis, psoriatic arthritis and ankylosing spondylitis.
M. Fauny +8 more
semanticscholar +1 more source
International Journal of Occupational Medicine and Environmental Health, 2020 Objectives Venom immunotherapy (VIT) is an effective treatment method and is addressed to patients with a history of an anaphylactic reaction to Hymenoptera stings. However, the immunological mechanisms of protection have not been explained yet.
Krzysztof Pałgan +3 more
doaj +1 more source
Journal of Investigative Surgery, 2021 Background Idiopathic Granulomatous Mastitis (IGM) is a benign chronic inflammatory breast disease that mimics breast cancer, and the etiopathogenesis has not yet been fully evaluated. Autoimmunity has received the most focus as a possible etiology.
Mehmet Saydam +8 more
doaj +1 more source
Interleukin-17: A Revisited Study [PDF]
International Journal of Immunopathology and Pharmacology, 2004 Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses.
HUANG SH +14 more
openaire +3 more sources