Results 71 to 80 of about 3,159,504 (378)
Inhibition of interleukin-17 in patients with oligoarticular psoriatic arthritis [PDF]
, 2023 Introduction: This study evaluated the efficacy of the interleukin-17A inhibitor secukinumab in patients with oligoarticular psoriatic arthritis (PsA). Methods: A total of 84 patients with oligoarticular PsA, defined as 1–4 tender joints and 1–4 swollen
Coates, Laura C +5 more
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Expressions of IL-17, IL-21 and IL-23 in the serum of allergic rhinitis patients [PDF]
Journal of Medical Biochemistry, 2011 The present study aimed to investigate the expressions of interleukin-17 (IL-17), IL-21 and IL-23 in the serum of allergic rhinitis (AR) patients and to explore their relationship with special IgE (sFgE) in the serum.
Huang Xuekun +5 more
doaj
Journal of Infection in Developing Countries, 2019 Introduction: Immune response to genital Chlamydia trachomatis infection is involved in both immunity and pathology. The cytokine profile during infection has been implicated in the disease outcome, either resolution or severe sequelae.
Alessandra Bua +3 more
doaj +1 more source
Cold Spring Harbor Perspectives in Biology, 2018 The cytokines of the interleukin 17 (IL-17) family play a central role in the control of infections, especially extracellular fungi. Conversely, if unrestrained, these inflammatory cytokines contribute to the pathology of numerous autoimmune and chronic ...
L. Monin, S. Gaffen
semanticscholar +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Science immunology, 2019 Interleukin-17 receptor D serves as a functional receptor for Interleukin-17A in psoriasis-like skin inflammation. A new receptor for interleukin-17 The cytokines interleukin-17A (IL-17A) and IL-17F drive immune activation by binding to the IL-17 ...
Yang Su +9 more
semanticscholar +1 more source
Arthritis Is Developed in Borrelia-Primed And -Infected Mice Deficient of Interleukin-17 [PDF]
, 2016 Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice ...
Kuo, Joseph +4 more
core +1 more source
Recovery of interleukin-17 production from interleukin-15-stimulated CD4+ mononuclear cells in HIV-1-infected patients with sustained viral suppression [PDF]
, 2014 Interleukin-17 (IL-17) is a pro-inflammatory cytokine that is mainly produced by CD4 + T cells. The role of Th17 during the human immunodeficiency virus (HIV)-1 infection is still unclear, but HIV-1 infection can cause a preferential depletion of Th17 ...
ASCOLI BARTOLI, Tommaso +9 more
core +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source