Results 251 to 260 of about 5,516,346 (290)
Some of the next articles are maybe not open access.
A highly sensitive and selective impedimetric aptasensor for interleukin-17 receptor A
Biosensors and Bioelectronics, 2016Interleukin-17 receptor A (IL-17RA) has been recognized as a valuable biomarker for diverse diseases, including autoimmune diseases. In this work, an electrochemical biosensor with great sensitivity and selectivity toward IL-17RA was fabricated using an IL-17RA aptamer (Kd=14.00nM) for the first time.
Hunho Jo +9 more
openaire +3 more sources
European Journal of Cancer, 2014
Material and Methods: To evaluate the extent of ITH in colorectal cancer (CRC) with microsatellite instability (MSI), we obtained 4−7 biopsies from 39 CRCs followed by MSI analysis either using the Bethesda MSI evaluation system or Promega system with 5 mononucleotide markers.
Y. Eun, H. Chung, Y.C. Lee
openaire +1 more source
Material and Methods: To evaluate the extent of ITH in colorectal cancer (CRC) with microsatellite instability (MSI), we obtained 4−7 biopsies from 39 CRCs followed by MSI analysis either using the Bethesda MSI evaluation system or Promega system with 5 mononucleotide markers.
Y. Eun, H. Chung, Y.C. Lee
openaire +1 more source
Structural Insights into the Interleukin-17 Family Cytokines and Their Receptors
2019The IL-17 family in humans consists of six distinct cytokines (IL-17A-F) that can interact with five IL-17 receptors (IL-17RA-E). The interaction between these cytokines and their receptors are critical in mediating host defenses while also making major contributions to inflammatory and autoimmune responses as demonstrated through both in vitro and in ...
openaire +2 more sources
Journal of Investigative Medicine, 2006
Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
openaire +1 more source
Inflammatory bowel diseases (IBD) are characterized by recurrent inflammation in the gastrointestinal tract. Infiltration of CD4+ lymphocytes and neutrophils is one of the predominant features in IBD. Recently, interleukin (IL)-23 and the downstream T-cell derived cytokine IL-17 have been found to be elevated in IBD patients. However, the role of IL-17
Z. Zhang +4 more
openaire +1 more source
An Overview of Interleukin-17A and Interleukin-17 Receptor A Structure, Interaction and Signaling
Protein & Peptide Letters, 2015Interleukin-17A (IL-17A) and its receptor (IL-17RA) are prototype members of IL-17 ligand/receptor family firstly identified in CD4+ T cells, which comprises six ligands (IL-17A to IL- 17F) and five receptors (IL-17RA to IL-17RE). IL-17A is predominantly secreted by T helper 17 (Th17) cells, and plays important roles in the development of autoimmune ...
Krstić, Jelena +6 more
openaire +3 more sources
Functional characterization of interleukin 17 family members and their receptors in amphioxus
International Journal of Biological MacromoleculesThe interleukin 17 (IL17) cytokine family plays a crucial role in phylogenetically conserved immune defense mechanisms, broadly categorized into two distinct evolutionary lineages: the invertebrate-derived (i-type) and vertebrate-specific (v-type) IL17 homologs.
Haifeng, Li +7 more
openaire +2 more sources
Critical Role of Interleukin-17 and Interleukin-17 Receptor Signaling in Tnbs-Induced Colitis
Journal of Investigative Medicine, 2006Z. Zhang +4 more
openaire +1 more source