Results 21 to 30 of about 161,071 (201)
Interleukin 1-β, Interleukin-1 Receptor Antagonist, and Interleukin 18 in Children with Acute Spontaneous Urticaria [PDF]
, 2013 Very little is known about the role of interleukin-1β (IL-1β) and interleukin-18 (IL-18) in urticaria. Material and Methods. Serum levels of IL-1β, IL-1 receptor antagonist (IL-1RA), and IL-18 were measured in 56 children with urticaria and in 41 healthy
A. Kasperska-Zając +4 more
core +1 more source
Evaluation of the Interleukin-1 Receptor Antagonist and Immunoregulatory Interleukin-10 in the Middle Ear in Chronic Otitis Media With Effusion in Children With and Without Atopy [PDF]
Clinical and Experimental Otorhinolaryngology, 2016 Objectives The role of pro-inflammatory cytokines in the course of chronic otitis media with effusion (COME) has been documented. However, there are fewer studies on the action of anti-inflammatory cytokines in the middle ear. We sought determine whether
Beata Zielnik-Jurkiewicz +1 more
doaj +1 more source
IL1RN (interleukin 1 receptor antagonist) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2014 Review on IL1RN, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Gómez-Flores-Ramos, L +2 more
openaire +2 more sources
The interleukin-1 receptor antagonist influences interleukin-1 effects in rat and mouse
Mediators of Inflammation, 1992 In this work we have focused on the ability of interleukin-1 to induce an acute phase protein response and a degranulation of polymorphonuclear leukocytes in vivo.
P. Bjrök, K. Ohlsson
doaj +1 more source
Frontiers in Pharmacology, 2017 Background: Mesenchymal stem cells (MSCs) and their chondrogenic differentiation have been extensively investigated in vitro as MSCs provide an attractive source besides chondrocytes for cartilage repair therapies.
Nicole Armbruster +6 more
doaj +1 more source
Communications Biology, 2021 Tan, Lash et al. show that blocking the Interleukin-1 receptor promotes rapid wound closure in diabetic mice. They engineered a matrix binding form of Interleukin-1 receptor antagonist (IL-1Ra) that has the ability of precise localisation and retention ...
Jean L. Tan +7 more
doaj +1 more source
Antagonism of cytokine-induced eosinophil accumulation in asthma [PDF]
, 2012 Peer reviewedPublisher ...
Walsh, Garry M.
core +2 more sources
OncoImmunology, 2019 Bermekimab is a true human monoclonal antibody that targets interleukin-1alpa (IL-1α), an inflammation-mediating alarmin. IL-1 receptor antagonist (IL-1Ra) is a natural molecule that blocks IL-1α activity by occupying the IL-1 receptor.
Razelle Kurzrock +8 more
doaj +1 more source
Studying the Pharmacokinetics of Interleukin-1RA Mutants
Bioscientific Review, 2019 The two antagonists for interleukin-1 (IL-1) system are IL-1α, and IL-1β. IL-1 receptor antagonist (IL-1RA) is another naturally occurring non-competitive antagonist. All three antagonists are bound to two receptors that are IL-R1 and IL-1R2.
Iqra Khuzaima +4 more
doaj +1 more source
Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]
, 2014 Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A +7 more
core +2 more sources