Results 31 to 40 of about 30,614,581 (155)

Interleukin 1 receptor antagonist relation to cardiovascular disease risk in patients with rheumatoid arthritis

Scientific Reports, 2022
Interleukin (IL) 1, and its family member, IL-1 receptor antagonist (IL-1ra), are involved in the pathogenesis and inflammation perpetuation of patients with rheumatoid arthritis (RA).
Cristina Almeida-Santiago, Juan Carlos Quevedo-Abeledo, Vanesa Hernández-Hernández, Antonia de Vera-González, Alejandra Gonzalez-Delgado, Miguel Ángel González-Gay, Iván Ferraz-Amaro   +6 more
doaj   +1 more source

SUPERSEDED - Supplementary Figures: Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence

, 2019
## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2626 ## Supplementary Figures from the manuscript "Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti ...
McCulloch, Laura
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Crystals of soluble interleukin-1 receptor complexed with its natural antagonist reveal a 1:1 receptor-ligand complex [PDF]

, 1995
Interleukin-1 is a cytokine involved in the acute phase response against infection and injury. We obtained crystals of a complex of soluble, recombinant human interleukin-1 receptor and recombinant human interleukin-1 receptor antagonist, a naturally ...
Ann Akeson, Edoardo Sarubbi, Terry Bowlin, Bowlin, Terry, Sarubbi, Edoardo, Schreuder, Herman, Ronald W. Barrett, Stephen Yanofsky, Herman Schreuder, Adolfo Soffientini, Yanofsky, Stephen, Barrett, Ronald W., Chantal Tardif, Akeson, Ann, Soffientini, Adolfo, Tardif, Chantal   +15 more
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Interleukin-1 Receptor Antagonist Protects Newborn Mice Against Pulmonary Hypertension

Frontiers in Immunology, 2019
Pulmonary hypertension secondary to bronchopulmonary dysplasia (BPD-PH) represents a major complication of BPD in extremely preterm infants for which there are currently no safe and effective interventions.
Christine B. Bui, Christine B. Bui, Magdalena Kolodziej, Emma Lamanna, Kirstin Elgass, Arvind Sehgal, Arvind Sehgal, Ina Rudloff, Ina Rudloff, Daryl O. Schwenke, Hirotsugu Tsuchimochi, Maurice A. G. M. Kroon, Maurice A. G. M. Kroon, Steven X. Cho, Steven X. Cho, Anton Maksimenko, Marian Cholewa, Philip J. Berger, Philip J. Berger, Morag J. Young, Jane E. Bourke, James T. Pearson, James T. Pearson, Marcel F. Nold, Marcel F. Nold, Claudia A. Nold-Petry, Claudia A. Nold-Petry   +26 more
doaj   +1 more source

Association of the Interleukin-1 Receptor Antagonist Gene with Asthma [PDF]

American Journal of Respiratory and Critical Care Medicine, 2004
Abstract The interleukin-1 cluster on human chromosome 2q12-2q14 harbors various promising candidate genes for asthma and other inflammatory diseases. We conducted a systematic association study with single-nucleotide polymorphisms (SNPs) located in candidate genes situated in this cluster.
Gohlke H, T. Illig, M. Bahnweg, N. Klopp, E. Andrè, J. Altmueller, N. Herbon, M. Werner, M. Knapp, L. Pescollderungg, BONER, Attilio, MALERBA, Giovanni, PIGNATTI, Pierfranco, M. Wjist   +13 more
openaire   +3 more sources

Interpretation on the 2021 EULAR/American College of Rheumatology Points to Consider for Diagnosis, Management and Monitoring of the Interleukin-1 Mediated Autoinflammatory Diseases: Cryopyrin-Associated Periodic Syndromes, Tumour Necrosis Factor Receptor-Associated Periodic Syndrome, Mevalonate Kinase Deficiency, and Deficiency of the Interleukin-1 Receptor Antagonist

Xiehe Yixue Zazhi, 2023
Interleukin-1 mediated autoinflammatory diseases, a large class of autoinflammatory diseases characterized by increased release of interleukin-1 or activation of the interleukin-1 pathway, mainly include familial Mediterranean fever, cryopyrin-associated
ZHOU Yu, SONG Hongmei
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Human interleukin‐1 receptor antagonist is expressed in liver [PDF]

FEBS Letters, 1992
Using PCR and Northern blot analysis, an IL‐1 receptor antagonist specific transcript was amplified from HepG2‐ and liver mRNA, cDNA clones coding for IL‐1 receptor antagonist were isolated from a liver cDNA library and sequence comparison revealed complete identity with the secreted, monocytic form of IL‐1 receptor antagonist.
Steinkasserer, Alexander, Estaller, C., Weiss, Elisabeth H., Sim, Robert B.   +3 more
openaire   +3 more sources

Palosuran: clinical pharmacology of a urotensin-II receptor antagonist in type 2 diabetes mellitus [PDF]

, 2015
Type 2 Diabetes Mellitus (Type 2 DM) is a growing global public health threat, leading to a significant cost burden to society. Type 2 DM increases the risk of hypertension and associated macro- and microcardiovascular diseases, affecting the eyes ...
Sidharta, Patricia N.
core   +1 more source

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K., Dembowsky, Klaus, Romagnoli, B., G Spohn, Karpova, Darja, Patel, K., Chevalier, E., Levesque, J. P., E Chevalier, D Karpova, Patel, Kalpana, Spohn, Gabriele, Romagnoli, Barbara, Schulz, M., Wiercinska, Eliza, Chevalier, Eric, H Bonig, K Dauber, E Wiercinska, J P Levesque, Schulz, Miriam, Chudziak, D., K Dembowsky, Dauber, Katrin, Karpova, D., B Romagnoli, A R Pettit, Wiercinska, E., D Chudziak, Levesque, Jean-Pierre, Bönig, Halvard-Björn, Spohn, G., Pettit, Allison R., M Schulz, K Patel, Bonig, H., Pettit, A. R., Chudziak, Doreen, Dauber, K.   +38 more
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A new treatment for hip osteoarthritis: clinical evidence for the efficacy of autologous conditioned serum

Orthopedic Reviews, 2013
The purpose of the present study was to investigate the effect of intra-articular injections of autologous conditioned serum on human hip osteoarthritis and to test whether a potential treatment effect might be increased by additional injections of ...
Axel W.A. Baltzer, Martin S. Ostapczuk, Daniel Stosch, Florian Seidel, Markus Granrath   +4 more
doaj   +1 more source