Results 51 to 60 of about 30,614,581 (155)

IL1RN (interleukin 1 receptor antagonist) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2014
Review on IL1RN, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Gómez-Flores-Ramos, L, Torres-Flores, J, Gallegos-Arreola, MP   +2 more
openaire   +2 more sources

New strategies to control inflammatory synovitis: interleukin 15 and beyond [PDF]

, 2003
No abstract ...
Harnett, W., Liew, F.Y., McInnes, I. B., Harnett, M., Gracie, J.A.   +4 more
core   +1 more source

Interleukin Gene Marker for Febrile Seizures

Pediatric Neurology Briefs, 2002
The use of polymorphisms for interleukin IB (IL-1B) exon 5 and interleukin 1 receptor antagonist (IL-1Ra) as markers of susceptibility to febrile seizures was evaluated in Taiwanese children (group 1: 51 with febrile convulsions and group 2: 83 normal ...
J Gordon Millichap
doaj   +1 more source

Physiologic role of interleukin-1 receptor antagonist.

Arthritis research, 2000
Recent studies have described the spontaneous development of arthritis or vasculitis in IL-1 receptor antagonist (IL-1Ra) knockout mice bred on specific and different genetic backgrounds. The levels of both secreted and intracellular isoforms of IL-1Ra produced in the rheumatoid joint or in the arterial wall may not be adequate to effectively inhibit ...
Arend, William P, Gabay, Cem
openaire   +2 more sources

Use of Anakinra in Patients with Cryopyrin-Associated Periodic Syndromes and Other Autoinflammatory Diseases

Вопросы современной педиатрии, 2016
The article describes the main autoinflammatory syndromes as well as the key role of interleukin (IL) 1 in the pathogenesis of these diseases. It also presents the data on the experience of anakinra using (soluble IL-1 receptor antagonist) as well as the
Mikhail M. Kostik
doaj   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

The Allele 2 of the VNTR Polymorphism in the Gene That Encodes a Natural Inhibitor of IL-1β, IL-1RA Is Favorably Associated With Chronic Otitis Media [PDF]

Clinical and Experimental Otorhinolaryngology, 2018
Objectives Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation.
Maja Živković, Ivana Kolić, Snežana Jesić, Ana Jotić, Aleksandra Stanković   +4 more
doaj   +1 more source

Serum interleukin–1 receptor antagonist levels.

, 2015
Serum interleukin–1 receptor antagonist levels (pg/ml) before (-60 min.) and after (40 min.) placebo or anakinra administration. P = participant number.
Eleonora Seelig (402226), Mareike Cordes (810918), Arno Schmidt-Trucksäss (316414), Michael Coslovsky (123769), Katharina Timper (810917), Henner Hanssen (810919), Thierry M. Nordmann (810916), Marc Y. Donath (324904)   +7 more
core   +1 more source

Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse. [PDF]

PLoS ONE, 2011
Healing after acute myocardial infarction (AMI) is characterized by an intense inflammatory response and increased Interleukin-1 (IL-1) tissue activity. Genetically engineered mice lacking the IL-1 receptor (IL-1R1-/-, not responsive to IL-1) or the IL-1
Antonio Abbate, Fadi N Salloum, Benjamin W Van Tassell, Elena Vecile, Stefano Toldo, Ignacio Seropian, Eleonora Mezzaroma, Aldo Dobrina   +7 more
doaj   +1 more source

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension [PDF]

, 2011
Background: Endothelin-1 signalling plays an important role in pathogenesis of pulmonary hypertension. Although different endothelin-A receptor antagonists are developed, a novel therapeutic option to cure the disease is still needed.
Norbert Weissmann, Sydykov, Akylbek, Brandes, Ralf, Schermuly, Ralph T., Hossein A Ghofrani, Janssen, Wiebke, Seeger Werner, Ralf P Brandes, Neil Davie, Dahal, Bhola K., Davie, Neil, Janssen Wiebke, Davie Neil, Ghofrani Hossein A, Seeger, Werner, Cornitescu, Teodora, Brandes Ralf P, Cornitescu Teodora, Kosanovic, Djuro, Kojonazarov, Baktybek, Werner Seeger, Friedrich Grimminger, Ghofrani, Hossein Ardeschir, Grimminger, Friedrich, Dahal Bhola K, Djuro Kosanovic, Baktybek Kojonazarov, Teodora Cornitescu, Schermuly Ralph T, Sydykov Akylbek, Wiebke Janssen, Grimminger Friedrich, Akylbek Sydykov, Kojonazarov Baktybek, Weissmann Norbert, Himal Luitel, Luitel Himal, Ralph T Schermuly, Luitel, Himal, Weißmann, Norbert, Bhola K Dahal, Kosanovic Djuro   +41 more
core   +2 more sources