Results 21 to 30 of about 46,140 (235)

Periodontal diseases and adverse pregnancy outcomes. Present and future

Periodontology 2000, EarlyView., 2023
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis, Mark Ide, Mervi Gürsoy, Phoebus N. Madianos   +3 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice. [PDF]

PLoS ONE, 2009
Recent evidence suggests that interleukin-1beta (IL-1beta), which was originally identified as a proinflammatory cytokine, is also required in the brain for memory processes.
Virginie F Labrousse, Laurence Costes, Agnès Aubert, Muriel Darnaudéry, Guillaume Ferreira, Thierry Amédée, Sophie Layé   +6 more
doaj   +1 more source

The Second Transmembrane Domain of P2X7 Contributes to Dilated Pore Formation [PDF]

, 2013
Activation of the purinergic receptor P2X7 leads to the cellular permeability of low molecular weight cations. To determine which domains of P2X7 are necessary for this permeability, we exchanged either the C-terminus or portions of the second ...
A MacKenzie, A Surprenant, AN Shemon, B Gu, BC Suh, BJ Gu, BJ Gu, BM Saunders, BS Khakh, BS Khakh, C Andrei, C Marques-da-Silva, C Sun, C Virginio, Chengqun Sun, CP Lai, D Leon, D Zink, DS Emmett, DS Samways, E Adinolfi, E Bulanova, F Bretschneider, F Rassendren, G Girolomoni, H Gunosewoyo, HJ Bradley, HM Costa-Junior, HZ Hu, JS Wiley, K Schroder, KA Hillman, L Gudipaty, L Stokes, LC Denlinger, LC Denlinger, LE Browne, LH Jiang, LH Jiang, M Li, M Li, Michelle E. Heid, ML Gavala, ML Smart, MT Miras-Portugal, P Marin-Garcia, P Pelegrin, P Pelegrin, Peter A. Keyel, Pierre Bobé, Q Li, R Sluyter, RA North, Russell D. Salter, S Chaumont, S Kracun, S Locovei, S Penuela, S Roger, SD Ohlendorff, SD Silberberg, SL Fernando, SL Fernando, T Kawate, T Sugiyama, TM Egan, V Petrilli, W Duckwitz, Y Shinozaki   +68 more
core   +12 more sources

GINGIVAL TISSUE IL-1beta AND PGE2 LEVELS IN PATIENTS WITH CHRONIC PERIODONTITIS AFTER ADDITIONAL THERAPY WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS [PDF]

Journal of IMAB, 2010
Background: The understanding of the pathogenesis of periodontitis makes various progresses in the last decades. Today it is well known that the synthesis of high levels of pro-inflammatory mediators from gingival tissues in response to ...
Christina Popova, Antoaneta Mlachkova
doaj   +1 more source

Effects of N-acetylcysteine on the inflammatory response and bacterial translocation in a model of intestinal obstruction and ischemia in rats

Acta Cirúrgica Brasileira, 2023
Purpose: To evaluate effect of N-acetylcysteine (NAC) associated with Ringer lactate or hypertonic saline in inflammation and bacterial translocation on experimental intestinal obstruction (IO). Methods: Wistar rats was subjected to IO.
Rafael Izar Domingues da Costa, Joao Marcos da Silva Fischer, Roberto Rasslan, Marcia Kiyomi Koike, Edvaldo Massazo Utiyama, Edna Frasson de Souza Montero   +5 more
doaj   +1 more source

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases. [PDF]

PLoS Pathogens, 2009
The intraerythrocytic parasite Plasmodium -- the causative agent of malaria -- produces an inorganic crystal called hemozoin (Hz) during the heme detoxification process, which is released into the circulation during erythrocyte lysis.
Marina Tiemi Shio, Stephanie C Eisenbarth, Myriam Savaria, Adrien F Vinet, Marie-Josée Bellemare, Kenneth W Harder, Fayyaz S Sutterwala, D Scott Bohle, Albert Descoteaux, Richard A Flavell, Martin Olivier   +10 more
doaj   +1 more source

Interleukin 1-beta (Il-1β) polymorphism and orthodontics: a systematic review

Revista Facultad de Odontología Universidad de Antioquia, 2019
Introduction: the aim of this systematic review is to explore the published literature to analyze the relationship between polymorphism of interleukin 1-beta (IL-1β) and orthodontics.
Juan Fernando Aristizábal, Héctor Ríos, Diego Rey, María Antonia Álvarez, Beatriz Parra-Patiño, Mario Ortiz   +5 more
doaj   +1 more source

The Association Between Shift Work and Immunological Biomarkers in Nurses

Frontiers in Public Health, 2020
Objectives: Shift work is associated with several negative health effects. The underlying pathophysiological mechanisms are unclear, but low-grade inflammation has been suggested to play a role.
Bjørn Bjorvatn, Bjørn Bjorvatn, John Axelsson, John Axelsson, Ståle Pallesen, Ståle Pallesen, Siri Waage, Siri Waage, Øystein Vedaa, Øystein Vedaa, Kjersti M. Blytt, Kjersti M. Blytt, Hogne V. Buchvold, Bente E. Moen, Eirunn Thun   +14 more
doaj   +1 more source

IL-1beta processing in host defense: beyond the inflammasomes. [PDF]

PLoS Pathogens, 2010
Stimulation and release of proinflammatory cytokines is an essential step for the activation of an effective innate host defense, and subsequently for the modulation of adaptive immune responses.
Mihai G Netea, Anna Simon, Frank van de Veerdonk, Bart-Jan Kullberg, Jos W M Van der Meer, Leo A B Joosten   +5 more
doaj   +1 more source