Interleukin-1 blockade in recently decompensated systolic heart failure: study design of the recently decompensated heart failure anakinra response trial (RED-HART) [PDF]
, 2015 Heart Failure (HF) is a clinical syndrome characterized by dyspnea, fatigue, and poor exercise capacity due to impaired cardiac function. The incidence of HF is increasing and represents the leading cause of hospitalization in the United States among ...
Abbate Antonio +8 more
core +1 more source
Egyptian Journal of Medical Human Genetics, 2022 Background Chronic periodontitis (CP) is a prevalent infectious disease caused by an interplay between pathogens and immune responses. Gene polymorphisms are among the factors that affect susceptibility to CP.
Leila Saremi +5 more
doaj +1 more source
Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]
, 2005 Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N +4 more
core +1 more source
Relationship between IL-1β production and endodontic status of human periapical lesions [PDF]
Vojnosanitetski Pregled, 2017 Background/Aim. Apical periodontitis is mainly caused by bacterial infection within the root canal and periapical bone destruction which are prominent features of this lesion.
Popovska Lidija +6 more
doaj +1 more source
Intracellular Chloride Concentration Changes Modulate IL-1β Expression and Secretion in Human Bronchial Epithelial Cultured Cells [PDF]
, 2017 Cystic fibrosis (CF) is caused by mutations in the CFTR gene, which encodes a cAMP‐regulated chloride channel. Several cellular functions are altered in CF cells. However, it is not clear how the CFTR failure induces those alterations.
Clauzure, Mariangeles +6 more
core +1 more source
Production of interleukin 1beta by human hematopoietic progenitor cells. [PDF]
Journal of Clinical Investigation, 1996 The production of interleukin 1beta (IL-1beta) by human hematopoietic stem/progenitor cells was studied to explore the concept that these cells are not merely responders to stimuli from their microenvironment, but can themselves produce a powerful biomodulator.
K, Watari +5 more
openaire +2 more sources
Lack of Interleukin 1-beta Expression Following Orthodontic Induced Root Resorption [PDF]
Cell Journal, 2011 Objective: To determine the effect of orthodontic tooth movement on the expression ofinterleukin-1β mRNA in rats using RT-PCR.Materials and Methods: Sample consisted of eighteen 8-week-old male Wistar rats.
Massoud Seifi +4 more
doaj
European Journal of Inflammation, 2020 Several case-control studies have been performed in different populations to uncover the association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis.
Jiaxuan Qin, Jinchun Xing, Zonglong Cai
doaj +1 more source
Immunohistochemical Analysis of IL-1 Receptor 1 In the Discs of Patients with Temporomandibular Joint Dysfunction [PDF]
, 2018 Objective Temporomandibular joint dysfunction (TMD) may affect a patient’s quality of life, and one of the etiologies can be anterior disc displacement with reduction (ADDwR) and anterior disc displacement without reduction (ADDWoR).
Almeida, Luis Eduardo +8 more
core +2 more sources
iPSC model of human specific neuroinflammation in Alzheimer’s disease [PDF]
Alzheimers DementAbstract Background Alzheimer’s disease (AD) is a human specific neurodegenerative disorder characterized by loss of memory and cognitive functions associated with amyloid beta 1‐42 (Aβ1‐42) plaques and tau fibrils. In the brain, an elevated level of Aβ1‐42 leads to neuronal death, microglia activation and neuroinflammation.
Ihnatovych I +4 more
europepmc +2 more sources