Results 51 to 60 of about 46,140 (235)
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. [PDF]
, 2010 Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18. We elucidate here how host macrophages recognize F.
Alnemri, Emad S +12 more
core +3 more sources
Dibutyltin‐induced alterations of interleukin 1beta secretion from human immune cells [PDF]
Journal of Applied Toxicology, 2016 AbstractDibutyltin (DBT) is used to stabilize polyvinyl chloride plastics (including pipes that distribute drinking water) and as a de‐worming agent in poultry. DBT is found in human blood, and DBT exposures alter the secretion of tumor necrosis factor alpha and interferon gamma from lymphocytes.
Shyretha, Brown +2 more
openaire +2 more sources
Immunity, Inflammation and Disease, 2023 Objectives To explore pro‐inflammatory cytokines status in the tear fluid of patients with hyperuricemia and gout and its association with uric acid level.
Mian Wu +4 more
doaj +1 more source
Neutrophil Elastase Promotes Interleukin-1 beta Secretion from Human Coronary Endothelium [PDF]
, 2015 The endothelium is critically involved in the pathogenesis of atherosclerosis by producing pro-inflammatory mediators, including IL-1β. Coronary arteries from patients with ischemic heart disease express large amounts of IL-1β in the endothelium. However,
Aird +58 more
core +2 more sources
Optogenetic Stimulation Enhances Interleukin-1beta Levels in Cultured Neurons [PDF]
Biophysical Journal, 2011 The pro-inflammatory cytokine interleukin-1beta (IL-1) has a role in physiological regulation, e.g. sleep, and in pathology including the chronic inflammation associated sleep disorders and in the neuropathology of brain trauma, epilepsy and stroke. Sleep and inflammation are affected by cell activity. However, a mechanistic connection between specific
Sengupta, Parijat +3 more
openaire +1 more source
Cysteine redox potential determines pro-inflammatory IL-1beta levels.
PLoS ONE, 2009 BackgroundCysteine (Cys) and its disulfide, cystine (CySS) represent the major extracellular thiol/disulfide redox control system. The redox potential (E(h)) of Cys/CySS is centered at approximately -80 mV in the plasma of healthy adults, and oxidation ...
Smita S Iyer +7 more
doaj +1 more source
Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis. [PDF]
Diabetes, 2001 Imidazoline compounds have been considered for the treatment of type 2 diabetes. We have now investigated the effects of imidazolines on interleukin (IL)-1beta-induced beta-cell apoptosis and the signal transduction pathways involved. Inhibition of Ca2+ influx into beta-cells by D-600, a blocker of voltage-gated L-type Ca2+ channels, suppressed IL ...
С. В. Зайцев +6 more
openalex +3 more sources
Interleukin-1 receptor type 1 is over-expressed in neurons but not in glial cells within the rat superficial spinal dorsal horn in complete Freund adjuvant induced inflammatory pain [PDF]
, 2017 K
Antal, Miklós +10 more
core +1 more source
Interleukin 1beta in serum of women with preterm uterine contractions
Journal of Obstetrics and Gynaecology, 1997 Preterm delivery is a major obstetric and public health problem, accounting for 50-70% of all perinatal deaths. An enzyme-linked immunoassay (ELISA) test was used to determine serum interleukin 1b (IL-1b) levels in 32 women with preterm contractions compared with 26 women in term labour and 11 normal preterm pregnant women.
B, Kaplan +5 more
openaire +2 more sources
Balkan Journal of Medical Genetics, 2023 The purpose of the study is to determine the prevalence of interleukin (IL)-1A (rs1800587), IL-1B (rs1143634) and vitamin D receptor (VDR) (TaqI, rs731236) gene polymorphisms in the Turkish population and their association with Stage III Grade B/C ...
Özturk Özener H. +7 more
doaj +1 more source