Results 51 to 60 of about 23,391 (181)

Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain. [PDF]

PLoS ONE, 2010
BACKGROUND: Neuropathic pain is a highly debilitating chronic pain following damage to peripheral sensory neurons and is often resistant to all treatments currently available, including opioids.
Shigeo Hasegawa, Yuta Kohro, Miho Shiratori, Satoshi Ishii, Takao Shimizu, Makoto Tsuda, Kazuhide Inoue   +6 more
doaj   +1 more source

Biological Signatures of Inflammation Biomarkers Identified Using Data Reduction Methods in Adult Population: A Scoping Review Protocol

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Chronic inflammation contributes to various chronic diseases, emphasizing the need for reliable biomarkers for early detection and understanding its causes. Measuring chronic inflammation poses challenges since most biomarkers are influenced by both acute and chronic states and recent exposures.
Gary Sánchez‐Gordón, Elena Plans‐Beriso, Cristina Barahona‐López, Berta Anta, Oscar Millet, Pablo Fernández‐Navarro, Nerea Fernández de Larrea‐Baz, Adela Castelló‐Pastor   +7 more
wiley   +1 more source

Molecular Characterization of Interleukin-1Beta in the Tammar Wallaby (Macropus eugenii)

Journal of Veterinary Medical Science, 2010
Interleukin-1beta (IL-1β) plays a significant role in the onset and pathogenesis of inflammation in mammalian hosts. Although well characterized in a range of vertebrate species, little is known about this important cytokine in marsupial mammals. We report here the molecular cloning and characterization of IL-1β in the tammar wallaby (Macropus eugenii).
Young, Lauren J., Harrison, Gavan A.
openaire   +4 more sources

Albiflorin Relieves Intervertebral Disc Degeneration Through Inhibiting Nucleus Pulposus Cell via the p38 MAPK/NF‐κB Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background As a chronic musculoskeletal disorder, intervertebral disc degeneration (IDD) is a leading cause of low back pain. Inflammatory response plays a key role in the IDD progression. Albiflorin (AF), a bioactive compound derived from Paeonia lactiflora, exhibits anti‐inflammatory effects in various diseases. However, the effects of AF on
Kai Yang, Yanping Cheng, Dan Yang
wiley   +1 more source

Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis [PDF]

Rheumatology, 2002
Since ulcerative colitis and Crohn's disease, which are associated with ankylosing spondylitis (AS), have been found to be variably associated with the IL-1B and the IL-1RN genes encoding interleukin-1beta (IL-1beta) and the interleukin-1 receptor antagonist (IL-1ra), we have investigated whether these polymorphisms in IL-1B and IL-1RN are also ...
M, van der Paardt, J B A, Crusius, M A, García-González, P, Baudoin, P J, Kostense, B Z, Alizadeh, B A C, Dijkmans, A S, Peña, I E, van der Horst-Bruinsma   +8 more
openaire   +2 more sources

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang, Tu Huang, Yi‐hang Hao, Min Zheng, Xin‐hua Liang   +4 more
wiley   +1 more source

The effect of high-intensity functional training with thylakoid supplementation on interleukins-1beta and interleukins 8 in obese men [PDF]

Journal of Medicinal Plants
Background: Obesity is a widespread public health concern with a growing global prevalence, leading to an increased risk of chronic metabolic conditions.
Heidar EbadiAsl, Bahman Mirzaei, Arsalan Damirchi   +2 more
doaj  

Association of severity of COPD with IgE and interleukin-1beta

Monaldi Archives for Chest Disease, 2016
Background. Chronic obstructive pulmonary disease (COPD) is a pulmonary inflammatory disease characterised by airflow limitation. The role of various inflammatory mediators such as interleukin-1beta (IL-1β) and Immunoglobulin E (IgE) have been implicated
B. Singh, S. Arora, V. Khanna
doaj   +1 more source

Interleukin-1beta stimulates placental leucine aminopeptidase/oxytocinase expression in BeWo choriocarcinoma cells [PDF]

Molecular Human Reproduction, 2003
In addition to prostaglandins, inflammatory cytokines induce uterine contraction via oxytocin (OT). Placental leucine aminopeptidase (P-LAP), an oxytocinase that is identical to cystine aminopeptidase, destroys OT activity. Patients with spontaneous preterm delivery have higher concentrations of inflammatory cytokines and lower P-LAP activities than ...
Yoko, Ikoma, Seiji, Nomura, Tomomi, Ito, Yoshinari, Katsumata, Masayuki, Nakata, Kumi, Iwanaga, Mayumi, Okada, Fumitaka, Kikkawa, Koji, Tamakoshi, Tetsuo, Nagasaka, Masafumi, Tsujimoto, Shigehiko, Mizutani   +11 more
openaire   +2 more sources

Persistent Interleukin‐1β Elevation in Post‐COVID‐19 Patients: Findings From a Nationwide Registry Study in Japan

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
Post‐COVID‐19 patients show persistent elevation of interleukin‐1β compared to healthy controls, sustained over 9 months without normalization. This low‐grade inflammatory response suggests ongoing immune activation following SARS‐CoV‐2 infection, providing insights into potential mechanisms underlying post‐COVID‐19 neuropsychiatric symptoms and ...
Naoki Takamatsu, Hiroki Kimura, Mari S. Oba, Hiroyuki Chiba, Ikue Umemoto, Yuki Moriyama, Nobuaki Matsunaga, Shinichiro Morioka, Daisuke Mori, Kazuhiro Hara, Aya Ogura, Kazufumi Yoshida, Hirohisa Watanabe, Satoshi Maesawa, Masashi Ikeda, Masahisa Katsuno, Norio Ohmagari, Masaki Takao, Shinsuke Kito, Norio Ozaki, Hironori Kuga   +20 more
wiley   +1 more source