Results 111 to 120 of about 26,112,494 (338)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Expression of chicken interleukin-2(IL-2) in E. coli. and preparation of its polyclonal antibody

open access: yes浙江大学学报. 农业与生命科学版, 2003
Interleukin-2 (IL-2) is known to play a number of functions in the modulation of immunity. In this study the chicken IL-2 gene was cloned into a prokaryon vector pET-28b and the recipient cell of E. coli.
YU Lian   +4 more
doaj   +1 more source

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

open access: yesJournal of Immunology, 1985
With the use of an enzyme-linked immunoabsorbent assay to measure soluble human interleukin 2 receptors (IL 2R), certain human T cell leukemia virus I (HTLV I)-positive T cell lines were found to spontaneously release large quantities of IL 2R into ...
L. Rubin   +6 more
semanticscholar   +1 more source

Humphrey Center News: Fall 1989 v. 4, no. 2 [PDF]

open access: yes, 1989
Newsletter of the Hubert H.
Anthony, Richard P.   +1 more
core  

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall   +9 more
wiley   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

open access: yesArthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr   +5 more
wiley   +1 more source

SODIUM POLYPRENYL PHOSPHATE (PHOSPRENYL) EXERTS AN IL-2-DEPENDENT RESTORATIVE EFFECT UPON IN VIVO DTH INHIBITION

open access: yesМедицинская иммунология, 2014
. We have shown that polyprenyl phosphate (phosprenyl) competes with interleukin 2 for binding with serum γ-globulin. It was also demonstrated that phosprenyl restores delayed type hypersensitivity induced by Listeria monocytogenes, after its inhibition ...
S. M. Sobolev   +3 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah   +8 more
wiley   +1 more source

A novel dual mechanism-of-action bispecific PD-1-IL-2v armed by a “βγ-only” interleukin-2 variant

open access: yesFrontiers in Immunology
IntroductionInterleukin-2 (IL-2) is one of the first cytokines to be discovered as an immune agonist for cancer immunotherapy. Biased IL-2 variants had been discovered to eliminate Treg activation or enhance the tumor specific T cell cytotoxicity ...
Yongji Jiang   +7 more
doaj   +1 more source

PENGARUH LATIHAN SATRIA NUSANTARA TINGKAT PRADASAR-DASAR TERHADAP PENURUNAN HORMON STRESS (KORTISOL) [PDF]

open access: yes, 2006
This research study is aimed at revealing the influence of stressors in Satria Nusantara pre-elementary breathing exercise training towards the reduction of the level of stress hormone (Kartisol).
Fauzi, M. Si, Siswantoyo, Dr., M. Kes
core  

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