Results 91 to 100 of about 97,446,967 (252)

Interleukin-2 therapy in patients with HIV infection. [PDF]

, 2009
International audienceBACKGROUND: Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone.
LANE HC, Collins, G., Babiker, A, INSIGHT ESPRIT STUDY GROUP, WENTWORTH D, Lundgren, J D, ROUTY JP, Fox, L., MITSUYASU R, Lévy, Yves, A Babiker (13489939), Mitsuyasu, R., Routy, J P, Tambussi, G, M Fisher (9886829), LUNDGREN JD, TAMBUSSI G, Lane, H C, Fox, L, COLLINS G, Filice, G, LOSSO MH, Routy, J.,, M H Losso (13489954), Losso, M., H., J D Lundgren (13489990), Cooper, D. A., D A Cooper (13490032), CAGLIUSO, MARIA, H C Lane (16165676), Neaton, J. D., Neaton, J. D, Lundgren, J. D., PHILLIPS A, Darbyshire, J, Losso, M. H., Phillips, A., Routy, J., P., BABIKER A, EMERY S, D Wentworth (13490251), Darbyshire, J., Neaton, James, D., Emery, S, Losso, M.,, F Gordin (13489960), R Mitsuyasu (16165679), SILCAAT SCIENTIFIC COMMITTEE, Emery, S., J P Routy (16165682), Lane, H., C., Babilker, A., J Darbyshire (13490209), COOPER DA, DARBYSHIRE J, A Phillips (816918), Collins, G, Losso, M H, Lundgren, J., D., Tambussi, G., MURDACA, GIUSEPPE, Cooper, D., Levy, Y., Gordin, F, Neaton, J D, G Tambussi (13619023), Mitsuyasu, R, Y Lévy (16165673), Wentworth, D., Lundgren, J.,, Lane, H.,, FOX L, Neaton, James,, NEATON JD, GORDIN F, CONTI, VALENTINA, J D Neaton (13490050), Cooper, D A, Lévy, Y, Routy, J. P., Abrams, D, D Abrams (13398651), LÉVY Y, Abrams, Donald, Wentworth, D, Babiker, A., Gordin, F., Lane, H. C., S Emery (7719341), ABRAMS D, Abrams, D., G Collins (13280751), AIUTI, Fernando, Phillips, A, L Fox (13367124)   +94 more
core   +1 more source

Salivary Cytokine Profiles in Active Smokers: An Exploratory Cross-Sectional Study of IL-2, IL-6, and IL-8

Diagnostics
Background: Active smoking is recognized as a major risk factor for oral and systemic inflammatory disorders. Tobacco smoke can alter immune responses and modulate the production of pro-inflammatory cytokines, potentially contributing to periodontal ...
Efstathios Grammatikis, Liliana Sachelarie, Corina Laura Ștefănescu, Marius-Daniel Radu, Cristina Furnică, Raluca Ozana Chistol, Elena Șapte   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Soluble interleukin 2 receptor levels.

, 2019
Soluble interleukin 2 receptor levels.
Jelle R. Miedema (7512251), Willem A. Dik (5871578), Paul L. A. van Daele (6398810), Laura E. M. Eurelings (7512248), P. Martin van Hagen (7329032), Jan A. M. van Laar (3145434), Virgil A. S. H. Dalm (6004133)   +6 more
core   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda, Zsuzsa Gyorfy, Duda, Erno, Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Annette Ohnemus, Kaspers, Bernd, Gyorfy, Zsuzsa, Ohnemus, Annette, Bernd Kaspers   +10 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history

, 2009
Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family ...
M Kusel (10012535), PG Holt (14457411), A Bosco (13307889), K McKenna (9886307), G Zhang (7349387), PD Sly (14453628), J Rowe (9877307), N De Klerk (13369254)   +7 more
core  

Defective production of interleukin 2 in patients with Chagas' disease: purified IL-2 augments in vitro response in patients with chagasic cardiomyopathy

Memorias do Instituto Oswaldo Cruz, 1996
The production of interleukin 2 (IL-2) by peripheral blood mononuclear cells, from patients with different clinical forms of Chagas disease and healthy controls, was evaluated after stimulation with Trypanosoma cruzi antigen, PPD and PHA.
Luis Briceno, Walter Mosca
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

IL-2-mediated hepatotoxicity: knowledge gap identification based on the irAOP concept

Journal of Immunotoxicology
Drug-induced hepatotoxicity constitutes a major reason for non-approval and post-marketing withdrawal of pharmaceuticals. In many cases, preclinical models lack predictive capacity for hepatic damage in humans.
Luise A. Roser, Christina Sakellariou, Malin Lindstedt, Vanessa Neuhaus, Susann Dehmel, Charline Sommer, Martin Raasch, Thierry Flandre, Sigrid Roesener, Philip Hewitt, Michael J. Parnham, Katherina Sewald, Susanne Schiffmann   +12 more
doaj   +1 more source