CD28-induced costimulation of T helper type 2 cells mediated by induction of responsiveness to interleukin 4. [PDF]
Type 1 and type 2 cloned T helper (Th) cells are believed to require different antigen-presenting cell (APC)-derived costimuli for proliferation. In the case of Th1-cloned T cells, CD28 signaling costimulates production of autocrine interleukin 2 (IL-2).
McArthur, JG, Raulet, DH
core
Experience with the Use of High-Dose Interleukin-2 in the Treatment of 652 Cancer Patients
Steven A. Rosenberg+6 more
openalex +2 more sources
Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. [PDF]
N Nogueira+9 more
openalex +1 more source
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey+5 more
wiley +1 more source
Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]
Kaiser, Pete+2 more
core +1 more source
Function of bovine blood and mammary gland mononuclear cells during the nonlactating period [PDF]
Bovine mammary mononuclear cells have been shown previously to be hyporesponsive in various functional assays compared to blood mononuclear cells. Mammary mononuclear cell hyporesponsiveness may contribute to susceptibility of the bovine mammary gland to
Torre, Patrick Michael
core +1 more source
Chronic granulomatous reaction in patients receiving vaccine immunotherapy for metastatic melanoma
Alexander B. Aria, BS+3 more
doaj +1 more source
The contribution of interleukin-2 to effective wound healing
K. M. Doersch+2 more
semanticscholar +1 more source
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley +1 more source
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou+4 more
wiley +1 more source