Results 171 to 180 of about 22,658,854 (391)

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

The contribution of interleukin-2 to effective wound healing

Experimental biology and medicine, 2017
K. M. Doersch, Daniel J DelloStritto, M. Newell-Rogers   +2 more
semanticscholar   +1 more source

Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. [PDF]

, 1981
David Wofsy, Edwin D. Murphy, J B Roths, Michael J. Dauphinée, Sophie Kipper, Norman Talal   +5 more
openalex   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Increasing Regulatory T Cells With Interleukin-2 and Interleukin-2 Antibody Complexes Attenuates Lung Inflammation and Heart Failure Progression

HYPERTENSION, 2016
Huan Wang, Lei Hou, Dongmin Kwak, J. Fassett, Xin Xu, A. Chen, W. Chen, B. Blazar, Yawei Xu, Jennifer L. Hall, Jun-bo Ge, R. Bache, Yingjie Chen   +12 more
semanticscholar   +1 more source

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression. [PDF]

, 1986
John C. Reed, Ammaar H. Abidi, James D. Alpers, R G Hoover, R J Robb, Peter C. Nowell̀   +5 more
openalex   +1 more source

Interferon Alfa in the treatment of B-cell chronic lymphocytic leukemia [PDF]

, 1994
Adolf, D., Bergmann, L., Dietzfelbinger, H., Emmerich, B., Knauf, W. U., Langenmayer, Irmgard, Maubach, P. A., Mitrou, P. S., Nerl, C., Thiel, E., Ziegle-Heitbrock, H. W. L.   +10 more
core   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia

, 1987
M Maeda, Nobuyoshi Arima, Y Daitoku, M Kashihara, Hisashi Okamoto, T Uchiyama, Kenji Shirono, Masao Matsuoka, Takamitsu Hattori, Kiyoshi Takatsuki   +9 more
openalex   +1 more source

Interleukin-2 [PDF]

, 2002
James W. Mier, Michael B. Atkins
openaire   +1 more source