Results 261 to 270 of about 22,658,854 (391)

Current landscape and future prospects of interleukin-2 receptor (IL-2R) agonists in cancer immunotherapy. [PDF]

Oncoimmunology
Tanigawa K, Redmond WL.
europepmc   +1 more source

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

Advanced Science, EarlyView.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville, Charlotte M. Fonta, Cornelia Leo, Lucine Christe, Jörg Goldhahn, Gad Singer, Viola Vogel   +6 more
wiley   +1 more source

A Case of Esophageal Cancer With Markedly Elevated Soluble Interleukin-2 Receptor: A Potential of Soluble Interleukin-2 Receptor as a Biomarker. [PDF]

Cureus
Seto N, Miura K, Jin L, Nakahara M.
europepmc   +1 more source

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

Advanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef, Léa Jabbour, Nassima Bekaddour, Giulio Avveduto, Nathalie Luciani, Gautier Laurent, Rana Bazzi, Edouard Alphandery, Stéphane Roux, Amanda K. A. Silva, Kelly Aubertin, Jean‐Philippe Herbeuval, Florence Gazeau   +12 more
wiley   +1 more source

Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/STAT5 signalling pathways

Immunology, 2012
Seon-Yeong Lee, M. Cho, H. Oh, J. Ryu, Min-jung Park, J. Jhun, Mi-Kyung Park, J. Stone, Ji‐hyun Ju, Sue‐Yun Hwang, Sung-Hwan Park, C. Surh, Ho‐Youn Kim   +12 more
semanticscholar   +1 more source

SHR-1916: A Novel PEGylated Interleukin-2 Analogue with Altered Cellular Selectivity and Improved Pharmacokinetic Profiles for Cancer Immunotherapy. [PDF]

Drug Des Devel Ther
Kong X, Lin Y, Ouyang C, Chen H, Gao X.
europepmc   +1 more source

The clinical potential of interleukin-2 [PDF]

British Journal of Cancer, 1988
openaire   +3 more sources

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

Interleukin-2-induced skin inflammation. [PDF]

Eur J Immunol
Sommer C, Cohen JN, Dehmel S, Neuhaus V, Schaudien D, Braun A, Sewald K, Rosenblum MD.   +7 more
europepmc   +1 more source

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

, 1984
Shimon Efrat, Raymond Kaempfer
openalex   +1 more source