Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease. [PDF]
Rafeek RAM+4 more
europepmc +1 more source
Cloning, sequence, and expression of bovine interleukin 2.
Douglas Pat Cerretti+7 more
openalex +1 more source
Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi+10 more
wiley +1 more source
The Diagnostic Value of Interleukin-2 and Interferon-γ Induced by Fusion Protein (ESAT-6/CFP-10/Rv1985c) for Active Mycobacterium tuberculosis Infection. [PDF]
Zhao Z+7 more
europepmc +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
[Biological activity and antitumor effect of long-acting recombinant human interleukin-2 drug]. [PDF]
Liang X, Zhang F, Jin T, Zhu J.
europepmc +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu+9 more
wiley +1 more source
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice. [PDF]
Moon S+6 more
europepmc +1 more source